Blood (Chapter 17)

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Over ____________ dissolved solutes in blood

100

Globin

4 polypeptide chains

Albumin

60% of plasma proteins

What percentage of body weight does blood make

8%

When neither anti-A serum nor anti-B serum cause clumping of donor cells, the blood type is: A. O B. B C. AB D. A

A

Which of the choices below is the parent cell for all formed elements of blood? A. Hemocytoblast B. Polymorphonuclear cell C. Megakaryocyte D. Normoblast

A

A person who lacks agglutinogen A, but has agglutinogen B would have blood type: A. O B. B C. AB D. A

B

Universal donor blood type A. AB B. O C. B D. A

B

What is the average normal pH range of blood? A. 4.65-4.75 B. 7.35-7.45 C. 7.75-7.85 D. 8.35-8.45

B

Which granulated leukocyte is most likely to be active during a bacterial infection? A. Basophils B. Neutrophils C. Monocytes D. Lymphocytes

B

Which leukocyte might you expect to find in higher quantities in a person experiencing allergies? A. Neutrophil B. Eosinophil C. Lymphocyte D. Basophil

B

Hemostasis is important for: A. RBC production B. WBC production C. Stoppage of bleeding D. RBC recycling

C

Which of the following would NOT lead to a bleeding disorder? A. Thrombocytopenia B. Impaired liver function C. Excess calcium in diet D. Vitamin K deficiency

C

Which two factors below make rapid and substantial blood loss life threatening? A. Loss of immunity, carbon dioxide carrying capacity B. Loss of immunity, BP C. Loss of BP, oxygen carrying capacity D. Loss of clotting ability, osmotic pressure

C

With a patient that is administered an injection of erythropoietin (EPO) you would expect to see: A. Increased WBC count B. Decreased hematocrit C. Increased hematocrit D. Decreased WBC count

C

Which ABO blood type is considered to be the universal recipient? A. A B. O C. B D. AB

D

formed elements (3)

Erythrocytes (RBC) Leukocytes (WBC) Platelets

Hemocytoblast

Give rise to all formed elements

Genesis of platelets Hannah Montana put macarony plate

Hemocytoblast Megakaryoblast Promegakaryocyte Megakarycyte Platelets

Erythropoiesis

Hemocytoblast Proerythroblast Early erythroblast Late erythroblast Normoblast (2) Reticulocyte Erythrocyte

Agranulocytes (2)

Lymphocytes Monocytes

Granulocytes (3)

Neutrophils (infection) Eosinophils (inflammation) Basophils

How does blood color vary

O2 content

Erythrocyte characteristics (3)

Small diameter Biconcave/anucleate/no organelles Filled w/ hemoglobin (Hb) for gas transport

Centrifuged blood consists of 3 layers

Top: plasma (55%) Buffy coat (<1%): WBC's/platelets Bottom: erythrocytes (45%)

All lymphocytes are leukocytes, but not all leukocytes are lymphocytes. T/F?

True

Blood is the only fluid tissue in the body. T/F?

True

Leukopenia is an abnormally low number of leukocytes. T/F?

True

Mature erythrocytes lack a nucleus. T/F?

True

Hemostasis Events (3)

Vascular spasm (vasoconstriction) Platelet plug formation Coagulation (form clot)

Diapedesis

WBC leave capillaries

Amoeboid Motion/Positive chemotaxis

WBC move through tissue spaces

Hemoglobin (Hb)

binds reversibly w/ oxygen red heme bound to protein globin

WBC function

defense against disease

Hematopoiesis

formation of all blood cells

Bone marrow is where ____________ takes place

hematopoiesis

Hemocytoblasts or

hematopoietic stem cells

formed elements

living blood cells

plasma

nonliving fluid

Hematocrit

percent of blood volume that is RBC's Norms F: 42% M: 47%


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