CHAPTER 8: REVIEW EXERCISE
Means "enzyme"
-ase
Tissue plasminogen activator drugs
-ase
Heparin and low molecular weight heparin
-parin
Direct thrombin inhibitor drugs
-rudin
Factor Xa inhibitor drugs
-xaban
Use the image to answer the following questions: ( WARFARIN) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?
1. generic 2. anticoagulant 3. to prevent a blood clot
Use the image to answer the following questions: (HEPARIN SODIUM) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?
1. generic 2. anticoagulant 3. to prevent a blood clot
Use the image to answer the following questions: (FOLIC ACID) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?
1. generic 2. vitamin 3. folic acid deficient anemia
List six foods that decrease the therapeutic effect of the oral anticoagulant drug warfarin (Coumadin, Jantoven).
1. leafy green vegetables (broccoli, Brussel sprouts, asparagus, spinach, bok choi, kale, parsley, and turnip greens) 2. lentils 3. liver 4. garbanzo beans (chickpeas) 5. hummus 6. green tea 7. soy milk 8. tofu
Use the image to answer the following questions: (ELIQUIS) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?
1. trade 2. factor Xa inhibitor 3. to prevent a blood clot
Use the image to answer the following questions: (SLOW FE) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?
1. trade 2. iron supplement 3. iron deficient anemia
The most common type of hemophilia is hemophilia ______, which is a deficiency of clotting factor ________.
A VIII
bivalrudin
Angiomax
_____________ drugs are used to prevent a blood clot from forming.
Anticoagulant
clopidogrel
Antiplatelet
warfarin
Coumadin
Nascobal
Cyanocobalamin
aspirin
Ecotrin
apixaban
Eliquis
epoetin alfa
Epogen
Folic acid dietary supplements are used to treat folic acid deficiency anemia.
False
Synergism is a drug-food interaction that decreases the drug's therapeutic effect.
False
The blood clotting factors are activated in numeral order to form a blood clot.
False
The cause of sickle cell anemia is chronic alcoholism.
False
Thrombolytic drugs can prevent a blood clot from forming.
False
The chemical symbol for iron is
Fe
ferrous fumarate
Femiron
What is the name of the B vitamin drug that is used to treat megaloblastic anemia?
Folic Acid
Siklos
Hydroxyurea
What are the effects of hydroxyurea in treating sickle cell anemia?
Hydroxyurea increases water content to maintain the shape of the RBC and increases hemoglobin F which is not prone to sickling.
What is the route of administration for delivering vitamin K to a newborn infant?
IM
Fe
Iron
The liver needs vitamin ______ to produce clotting factors.
K
clopidogrel
Plavix
Siklos
Sickle cell drug
Aspirin is the least expensive of all the antiplatelet drugs.
True
The antiseizure drug Dilantin and the antibiotic drug Bactrim have a tendency to cause folic acid deficiency anemia.
True
Most drugs to treat pernicious anemia are given by injection. What is unique about Nascobal?
administered as a nasal spray
Activase
alteplase
Plavix
antiplatelet
aspirin
antiplatelet
Eliquis
apixaban
Heparin is a natural anticoagulant substance released from
basophils
antiplatelet
block various receptors on the surface of platelets to prevent platelet aggregation.
Plavix
clopidogrel
Which is the first antiplatelet drug approved by the FDA?
clopidogrel (Plavix)
Fragmin
dalteparin
DVT
deep-venous thrombosis
bivalrudin
direct thrombin inhibitor
Procrit
epoetin alfa
a drug created using recombinant DNA technology
epoetin alfa
Stimulating the red bone marrow to make more red blood cells is the process of
erythropoiesis
Procrit
erythropoiesis-stimulating drug
epoetin alfa
erythropoiesis-stimulating drug
a hormone produced by the kidneys
erythropoietin
Eliquis
factor Xa inhibitor
Xarelto
factor Xa inhibitor
apixaban
factor Xa inhibitor
The FDA requires flour and grain products to have added _____________ as a supplement to prevent neural tube defects in newborn babies.
folic acid
Why was low molecular weight heparin created?
for better absorption and better therapeutic effect
Name one food that increases its therapeutic effect.
garlic
Plavix should not be taken with ______ or its juice.
grapefruit
direct thrombin inhibitor
inhibit the action of thrombin by binding to receptor sites on thrombin.
ferrous fumarate
iron deficiency drug
Fragmin
low molecular weight heparin
PE
pulmonary embolism
Antiplatelet drugs block different kinds of _________ on the surface of platelets.
receptors
When discussing antihemophilic factor VIII as a drug, identify the meaning of the following: RECOMBINANT
referres to the method by which the drug antihemophilic factor VIII is created.
Xarelto
rivaroxaban
When discussing antihemophilic factor VIII as a drug, identify the meaning of the following: PEGYLATED
the process in which polyethylene glycol (PEG) is attached to the factor VIII drug to increase the amount of time it is active in the blood and decrease its excretion by the kidneys.
Activase
tissue plasminogen activator
tPA
tissue plasminogen activator
Why is a vitamin K drug given to newborn infants?
to prevent hemorrhage
Doses of heparin are measured in
units
Nascobal
vitamin B12
Jantoven
vitamin K antagonist
warfarin
vitamin K antagonist
Jantoven
warfarin