CHAPTER 8: REVIEW EXERCISE

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Means "enzyme"

-ase

Tissue plasminogen activator drugs

-ase

Heparin and low molecular weight heparin

-parin

Direct thrombin inhibitor drugs

-rudin

Factor Xa inhibitor drugs

-xaban

Use the image to answer the following questions: ( WARFARIN) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?

1. generic 2. anticoagulant 3. to prevent a blood clot

Use the image to answer the following questions: (HEPARIN SODIUM) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?

1. generic 2. anticoagulant 3. to prevent a blood clot

Use the image to answer the following questions: (FOLIC ACID) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?

1. generic 2. vitamin 3. folic acid deficient anemia

List six foods that decrease the therapeutic effect of the oral anticoagulant drug warfarin (Coumadin, Jantoven).

1. leafy green vegetables (broccoli, Brussel sprouts, asparagus, spinach, bok choi, kale, parsley, and turnip greens) 2. lentils 3. liver 4. garbanzo beans (chickpeas) 5. hummus 6. green tea 7. soy milk 8. tofu

Use the image to answer the following questions: (ELIQUIS) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?

1. trade 2. factor Xa inhibitor 3. to prevent a blood clot

Use the image to answer the following questions: (SLOW FE) 1. Is the drug shown a generic or trade name drug? 2. To what drug class does the drug shown belong? 3. What is this used to treat?

1. trade 2. iron supplement 3. iron deficient anemia

The most common type of hemophilia is hemophilia ______, which is a deficiency of clotting factor ________.

A VIII

bivalrudin

Angiomax

_____________ drugs are used to prevent a blood clot from forming.

Anticoagulant

clopidogrel

Antiplatelet

warfarin

Coumadin

Nascobal

Cyanocobalamin

aspirin

Ecotrin

apixaban

Eliquis

epoetin alfa

Epogen

Folic acid dietary supplements are used to treat folic acid deficiency anemia.

False

Synergism is a drug-food interaction that decreases the drug's therapeutic effect.

False

The blood clotting factors are activated in numeral order to form a blood clot.

False

The cause of sickle cell anemia is chronic alcoholism.

False

Thrombolytic drugs can prevent a blood clot from forming.

False

The chemical symbol for iron is

Fe

ferrous fumarate

Femiron

What is the name of the B vitamin drug that is used to treat megaloblastic anemia?

Folic Acid

Siklos

Hydroxyurea

What are the effects of hydroxyurea in treating sickle cell anemia?

Hydroxyurea increases water content to maintain the shape of the RBC and increases hemoglobin F which is not prone to sickling.

What is the route of administration for delivering vitamin K to a newborn infant?

IM

Fe

Iron

The liver needs vitamin ______ to produce clotting factors.

K

clopidogrel

Plavix

Siklos

Sickle cell drug

Aspirin is the least expensive of all the antiplatelet drugs.

True

The antiseizure drug Dilantin and the antibiotic drug Bactrim have a tendency to cause folic acid deficiency anemia.

True

Most drugs to treat pernicious anemia are given by injection. What is unique about Nascobal?

administered as a nasal spray

Activase

alteplase

Plavix

antiplatelet

aspirin

antiplatelet

Eliquis

apixaban

Heparin is a natural anticoagulant substance released from

basophils

antiplatelet

block various receptors on the surface of platelets to prevent platelet aggregation.

Plavix

clopidogrel

Which is the first antiplatelet drug approved by the FDA?

clopidogrel (Plavix)

Fragmin

dalteparin

DVT

deep-venous thrombosis

bivalrudin

direct thrombin inhibitor

Procrit

epoetin alfa

a drug created using recombinant DNA technology

epoetin alfa

Stimulating the red bone marrow to make more red blood cells is the process of

erythropoiesis

Procrit

erythropoiesis-stimulating drug

epoetin alfa

erythropoiesis-stimulating drug

a hormone produced by the kidneys

erythropoietin

Eliquis

factor Xa inhibitor

Xarelto

factor Xa inhibitor

apixaban

factor Xa inhibitor

The FDA requires flour and grain products to have added _____________ as a supplement to prevent neural tube defects in newborn babies.

folic acid

Why was low molecular weight heparin created?

for better absorption and better therapeutic effect

Name one food that increases its therapeutic effect.

garlic

Plavix should not be taken with ______ or its juice.

grapefruit

direct thrombin inhibitor

inhibit the action of thrombin by binding to receptor sites on thrombin.

ferrous fumarate

iron deficiency drug

Fragmin

low molecular weight heparin

PE

pulmonary embolism

Antiplatelet drugs block different kinds of _________ on the surface of platelets.

receptors

When discussing antihemophilic factor VIII as a drug, identify the meaning of the following: RECOMBINANT

referres to the method by which the drug antihemophilic factor VIII is created.

Xarelto

rivaroxaban

When discussing antihemophilic factor VIII as a drug, identify the meaning of the following: PEGYLATED

the process in which polyethylene glycol (PEG) is attached to the factor VIII drug to increase the amount of time it is active in the blood and decrease its excretion by the kidneys.

Activase

tissue plasminogen activator

tPA

tissue plasminogen activator

Why is a vitamin K drug given to newborn infants?

to prevent hemorrhage

Doses of heparin are measured in

units

Nascobal

vitamin B12

Jantoven

vitamin K antagonist

warfarin

vitamin K antagonist

Jantoven

warfarin


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