Hematology Test
HUS Hemolytic uremic syndrome
scattered schistocytes and helmet cells
In flow cytometry, the granularity of a cell is indicated by which of the following?
side scatter
Which of the following tests would be most affected by microclots in an EDTA tube drawn for a CBC?
Platelet count
What cellular characteristic of red blood cells is described by the term poikilocytosis?
Variability in shape
All of the following would be situations where you would typically find an increase in eosinophils EXCPET?
Viral infections
normal mature lymphocytes are associated with
Viral meningitis
Which of the following is considered to be the stain of choice for evaluation of peripheral blood smear to include red cell morphology as well as a white cell diff count
Wrights
The appropriate magnification for a manual RBC cell count using a hemoctometer is which of the following
40X Dry
How many large hemacytometer squares contain a total volume of 1 microliter of fluid
10
What is the corrected white blood cell count if the WBC is 14,460 and there were 47 nucleated RBC per 100 WBCs noted on the diff
9,837
Which of the following options best describes how hemophilia A differs from hemophilia B?
A is Factor VIII and B is Factor IX
What is one of the main characteristics of secondary granules in the neutrophilic granulocyte cytoplasm?
Appear first at the myelocyte stage
Methylene blue stain works by
Staining cellular components that have an acidic pH such as ribosomes, DNA, and RNA
RBCs with what is looks like little mouths
Stomatocytes
Low LAP results are associated with what disease?
CML chronic myelogenous leukemia
Reactive lymphocytes associated with
Infectious mononucleosis
All of the following conditions are associated with hereditary spherocytosis, Except??
Intravascular hemolysis
Two types of population of RBC why does that happen?
Transfusion dimorphism
Auer rods are most commonly present in which of the following conditions
Acute myelocytic leukemia AML
What is the compostion of basophilic stippling?
Aggregation of ribosomes
Pelger-Huet anomaly is characterized by which of the following?
Bilobed or round nuclei in neutrophils (hyposegmented)
All of the following CD markers are present on a normal mature T cell EXCEPT
CD20
Which ethnic group has the highest incidence of hereditary hemochromatosis in the United States?
Caucasians
What are Howell-Jolly bodies composed of?
DNA
Which of the following would describe hypochromia?
Decreased hemoglobin concentration in RBCs
When performing controls for the morning run in coagulation, the normal control is within acceptable limits for both PT and APTT but the abnormal control is out of range for both procedures. Which of the following would be an appropriate action to take
Document QC, repeat, troubleshoot, only can result PT when controls are in
Which of the following will cause a falsely increased erythrocyte sedimentation rate
ESR tube is slanted
All of the following are known causes of aplastic anemia EXCEPT?
Enzyme deficiencies
Which coagulation pathway is Factor VII part of?
Extrinsic
Which of the following factors is Vitamin K-dependent
Factor IX
Which of the following conditions will show an increased prothrombin time with a normal activated thromboplastin time
Factor VII deficiency
Hemophilia A is associated with a deficiency of which of the following?
Factor VIII
An alpha thalassemia PT is diagnosed as having three of their four genes deleted which code for alpha hemoglobin chains. Which of the following types of hemoglobin is abnormal and would be found in such a PT
Hb H
All of the following tests will be abnormal in a PT with Stuart-Prower Factor deficiency EXCEPT:
Fibrinogen
Which of the following conditions is associated with the defective erythrocytes that are indicated.
G6PD deficiency
Which hemoglobin when elevated acts as a protection against sickling in PT with HbS
Hemoglobin F
A quick math check which can be applied to verify that the hemoglobin and hematocrit values on a CBC correspond with each other would be:
Hemoglobin X 3 = hematocrit
The first time a cell containing HbSS is deoxygenated, it forms a sickle cell. Upon reoxygenation which of the following is true for the sickle cell?
It will return to a normal biconcave shape
Which lab procedure may be used to assist in differentiating chronic myelocytic leukemia from leukemoid reaction
LAP
Which of the following disorders or diseases is assoctitaed with coarse basophilic stippling?
Lead poisoning
Which of the following conditions would have macrocytic red cells?
Liver disease and Vitamin B12 deficiency
All of the following methods are used to detect and differentiate white blood cells in most hematology analyzers EXCEPT?
Lysis of white cells with subsequent conversion to hemiglobincyanide followed by colorimetric determination
Which of the following RBC indices is expressed in femtoliters?
MCV
Calculate the RBC indices from the following RBC C= 5.22 Hemo= 17.5 Hema= 53%
MCV: 102 MCH:34 MCHC:33 LOOK UP FORMU`LAS
Which of the marrows cells from the list below has highly granular basophilic cytoplasm but does not show nuclear lobules?
Mast cell
What is the precursor of the platelet which is commonly only found in the bone marrow?
Megakaryocyte
Hypersegmented neutrophils in the peripheral blood is indication of which of the following conditions?
Megaloblastic anemia
Which of the following conditions are Cabot rings most likely to be observed on a Wrights-stained peripheral blood smear
Megaloblastic anemia
After briefly circulating in the peripheral blood, which of the following cells becomes a tissue macrophages whose main function is phagocytosis?
Monocyte
Phagocytosis is a function of which of the following types of cell
Monocytes
Which of the following is a clinical symptom that is associated with thrombocytopenia
Petechiae
Field of RBCs that were stained using a supravital stain. How would these RBCs appear if they were viewed on a Wright stained smear?
Polychromatophilic RBCs
The site most frequently used to collect bone marrow samples from adults is
Posterior iliac crest
What is the correct order of erythrocytes maturation in the bone marrow?
Pronormoblast Basophilic normoblast polychromatophilic normoblast Orthochromic normoblast polychromatophilic erythrocyte
When scanning a Wright's stain blood smear, Which of the following would describe the optimum area to begin your blood smear analysis and diff?
RBCs are lying singly, barely touching, with occasional overlapping
What would be the next step when EDTA specimen has an automated PLT count of 61,000 and the PLT were surrounding the neutrophils on the differential?
Recollect a specimen for PLT count w/o using EDTA
Which of the following descriptions best describes the term absolute value as it would relate to leukocyte differential counts
Relative % of each cell type multiplied by total white count
The diagnostic value of the reticulocyte count in the evaluation of anemia is that it determines the
Response and ability of the bone marrow to compensate for the anemia
T lymphocytes are characterized by all of the following functions EXCEPT?
Synthesis antibody
What is the predominant abnormal erythrocyte morphology associated with idiopathic myelofibrosis?
Teardrop cells
Which of the following statements about macrocytes is true?
The cells are typically larger than a resting lymphocyte
All of the following bones contain active hematopoietic bone marrow in a normal adult EXCEPT?
Tibia
What are the expected results of the laboratory markers in iron deficiency anemia?
decreased serum iron, increased transferrin, decreased ferritin, decreased percent saturation, and increased total iron binding.
What is the correct procedure using a winged collection device to draw a light blue top tube intended for coagulation test if this is the first tube that will be collected in the draw
draw and discard a waste light-blue top tube before the tube that will be used for coagulation studies
Spherocytes are associated with which if the following conditions?
immune hemolytic anemia
