Table 48-7 (Drug therapy diabetes)
Metformin
( lactic acidosis)
canagliflozin dapagliflozin
(UTI)
linagliptin saxaglipin
(pancreatitis)
Bromocriptine
activates dopamine (orthostatic hypotension)
canagliflozin dapagliflozin
deceases renal glucose absorption lead to increased excretion.
Metformin
decreases hepatic glucose production. increase glucose uptake in muscles.
acarbose
delay absorption of complex carbohydrates
miglitol
delay absorption of complex carbohydrates
Pioglitazone Rosiglitazone
increase glucose uptake in muscle decrease endogenous glucose production decrease insulin resistance
pramlintide
slows gastric emptying decreases endogenous glucose output
Nateglinide Repaglinide
stimulate a rapid and short lived release of insulin
Glipizide Glyburide
stimulate release of insulin from pancreatic cells
linagliptin saxaglipin
stimulate release of insulin. decrease hepatic glucose. increatins
Exenatide liraglutide
stimulate release of insulin. slow gastric emptying.