Patho 2 ch 52
a clinical finding consistent with a diagnosis of rheumatoid arthritis is ___________
systemic manifestations of inflammation
Please explain the pathophysiology of osteoarthritis to me says a nurse. "is it just wear and tear so that the cartilage wears out?" your best response is _________
no, cells in bone, cartilage, synovial membrane all get activated and secrete inflammatory mediators that destroy cartilage and damage bone
a patient diagnosed with systemic Lupus erythematosus (SLE) is treated with low dose oral steroids to reduce joint inflammation during intermittent flare-ups. Steroids are used because they _____________
-effectively suppress a variety of immune responses
the chief pathologic features of osteoarthritis are ____________
-degeneration or articular cartilage -destruction of bone under the cartilage -thickening of the synovium
the final stage of gout, characterized by crystalline deposits in cartilage, synovial membranes, and soft tissue, is called _____________
Tophaceous gout
the pathophysiology of rheumatoid arthritis involves __________________
immune cells accumulating in pannus and destroying articular cartilage
individuals diagnosed with systemic lupus erythematosus (SLE) are at risk for developing numerous complications of various organs because of ________
immune injury to basement membranes
Gouty arthritis is a complication of
inadequate renal excretion of uric acid
systemic disorders include __________
rheumatoid arthritis
"tell me again the name of that chemical that makes crystals when my gout flares up" the nurses best response is _______
uric acid