Blood

Hemocytoblast

A type of stem cell from which all formed elements originate

Formed Elements

Cell fragments; include erythrocytes, thrombocytes, and leukocytes

Red Bone Marrow

Formed elements of blood are produced here. Site of formation and maturation of erythrocytes, thrombocytes, monocytes and granulocytes (neutrophils, basophils and eosinophils). Consists of network of reticular fibers, blood vessels and many cell types.

Lymphoid Stem Cells

Hemocytoblasts differentiate into ___ from which lymphocytes develop

Megakaryocytes

Hemocytoblasts differentiate into these giant cells that fragment in red marrow to produce thrombocytes (platelets). have a large, multi-lobed nucleus

Adipocytes

Large, nearly circular open areas.

Hemopoiesis

The process of producing formed elements of the blood

Monocyte

Type of agranulocyte, has lots of blue cytoplasm, 4-8%

Lymphocyte

Type of agranulocyte, has small amount of blue cytoplasm and forms light blue halo around nucleus, 20-45%

Basophil

Type of granulocyte, bi-lobed, has pink cytoplasm and large purple granules, 0-1%

Eosinophil

Type of granulocyte, bi-lobed, has pink cytoplasm and large reddish-orange granules, 1-4%

Neutrophil

Type of granulocyte, multi-lobed, has pink cytoplasm and the granules don't pick up stain, 40-70%

Stem Cell

a cell capable of producing daughter cells that can differentiate into other cell types

Differential White Blood Cell count

a determination of the percent of the different WBC types in a person's blood

Thrombocytes

aka platelets, not true cells but fragments derived from megakaryocytes located in red bone marrow. darkly stained, irregular-shaped objects. Play an essential role in hemostasis, or the stoppage of bleeding from a damaged blood vessel

Erythrocytes

aka red blood cells, have a binconcave disk shape thus appear paler in the center. The most numerous of the formed elements. Function to transport oxygen and carbon dioxide. Contain high content of hemoglobin and have an enzyme called carbonic anhydrase.

Leukocytes

aka white blood cells, nucleated unlike RBC's. Have five different types that help to protect the body against invasion by a wide variety of pathogens.

Plasma

an incredibly complex substance; the nonliving fluid matrix component of blood

Blood

consists of plasma and formed elements

Granulocyte

contains visible, stained granules in its cytoplasm

Agranulocyte

do not contain visible stained granules in its cyctoplasm

Myeloid Stem Cells

hemocytoblasts differentiate into ____ erythrocytes, granulocytes and monocytes develop

Sinusoid

major blood vessel in red bone marrow. formed elements enter into the bloodstream through its walls

4 - 6 million per cubic millimeter

normal RBC count for people living at sea level

4,000 - 11,000 per cubic millimeter

normal WBC count

250,000 - 500,000 per cubic millimeter

platelet count

Hematocrit

the percentage of whole blood that consists of formed elements