CITI- Conflicts of Interest

An investigator received $4,000 of consulting income from a publicly traded drug company over the past 12 months. The investigator also owns stock in that company valued at $2,000. The investigator is submitting a grant to the National Institutes of Health that involves evaluating the effectiveness of a drug produced by the same drug company. Which of the following is true? -The aggregate of the consulting income and the stock exceeds $5,000 and therefore is a significant financial interest. -The value of stock is not calculated when determining significant financial interests. -The investigator does not have a significant financial interest related to the grant because the stock's value is less than $5,000. -The investigator does not have a significant financial interest related to the grant because the consulting income is less than $5,000.

-The aggregate of the consulting income and the stock exceeds $5,000 and therefore is a significant financial interest.

Which of the following financial conflict of interest information must be made available by institutions on a public website or within five business days upon request? -The financial interests of all research administrators at an academic center. -The financial conflicts of interest of senior/key personnel on projects funded by the U.S. Public Health Service. -The financial interests of all faculty at an academic center. -The conflicts of commitment of researchers funded by the U.S. Public Health Service.

-The financial conflicts of interest of senior/key personnel on projects funded by the U.S. Public Health Service.

According to the U.S. Public Health Service, the definition of the term "investigator": -Includes anyone involved in the conduct or reporting of research. -Refers only to the principal investigator and laboratory technicians. -Includes faculty but not students. -Refers only to the principal investigator.

-Includes anyone involved in the conduct or reporting of research.

Within how many days of acquiring or discovering a significant financial interest is the investigator required to submit an updated disclosure to the institution? -365 days. -30 days. -90 days. -7 days.

-30 days.

According to the U.S. Public Health Service regulations, investigators are required to disclose travel sponsored or reimbursed by: -A U.S. institution of higher education. -A government agency. -An academic teaching hospital. -A publicly traded company.

-A publicly traded company.

Which of the following statements most accurately describes a mitigation report? -A report to the U.S. Public Health Service of efforts that will be taken by the institution to deal with any bias that was found in research conducted while there was an unreported financial conflict of interest. -A report from the U.S. Public Health Service to an institution of what must be done to deal with financial conflicts of interest of its PHS-funded researchers. -An annual report to the U.S. Public Health Service of all the significant financial interests of the institution's PHS-funded researchers. -A report from an institution telling the U.S. Public Health Service how bias will be minimized before a research project begins.

-A report to the U.S. Public Health Service of efforts that will be taken by the institution to deal with any bias that was found in research conducted while there was an unreported financial conflict of interest.

According to the U.S. Public Health Service, which of the following would be considered a significant financial interest? -Income from the university where the investigator is currently employed. -An equity interest valued at $10,000 or more that is not related to the investigator's institutional responsibilities. -An equity interest valued at $5,000 owned by the investigator's spouse in a company that produces products related to the investigator's institutional responsibilities. -Travel expenses reimbursed by a U.S. institution of higher education.

-An equity interest valued at $5,000 owned by the investigator's spouse in a company that produces products related to the investigator's institutional responsibilities.

Which of the following is true regarding the U.S. Public Health Service and its approach to the disclosure of significant financial interests? -Any equity interest contained in a retirement account must be disclosed. -Any income from a mutual fund must be disclosed. -Any equity interest owned by the investigator's cousins must be disclosed. -Any equity interest in a non-publicly traded company must be disclosed.

-Any equity interest in a non-publicly traded company must be disclosed.

The U.S. Public Health Service (PHS) requires institutions to: -Collect information about the significant financial interests of all faculty and staff. -Disclose their investigators' new financial conflicts of interest to the PHS awarding component within 60 days of discovering them. -Post the significant financial interests of all researchers to a publicly available website. -Block faculty from owning any equity interest in a company that sponsors research.

-Disclose their investigators' new financial conflicts of interest to the PHS awarding component within 60 days of discovering them.

Institutions are required by the U.S. Public Health Service to do which of the following: -Apply the same financial conflict of interest policy to all researchers regardless of their funding source. -Evaluate whether a significant financial interest is related to an investigator's research and constitutes a financial conflict of interest. -Update their financial conflict of interest policy every four years. -Eliminate any and all conflicts of interest.

-Evaluate whether a significant financial interest is related to an investigator's research and constitutes a financial conflict of interest.

At a minimum, how often are investigators funded by the U.S. National Institutes of Health required to receive conflict of interest training? -Every four years. -Once per career stage. -Every two years. -Annually.

-Every four years.

According to the U.S. Public Health Service, a "significant financial interest" includes royalty income paid to an investigator and its disclosure is required: -Regardless of the source of the income. -Only if it relates to income from governmental agencies. -Except if that income is from the institution that currently employs the investigator. -Only if it relates to income from publicly traded companies.

-Except if that income is from the institution that currently employs the investigator.

Which of the following statements is true regarding the reporting of outside interests and the management of conflicts? -Investigators must disclose all of their financial interests regardless of whether they are related to a research project. -Investigators are responsible for developing their own management plans for significant financial interests. -The institution must report identified financial conflicts of interest to the U.S. Office of Research Integrity. -Investigators must disclose their significant financial interests related to their institutional responsibilities and not just those related to a particular project.

-Investigators must disclose their significant financial interests related to their institutional responsibilities and not just those related to a particular project.

Which of following most accurately describes when investigators pursuing U.S. Public Health Service funding are required to disclose their significant financial interests to their institution? -Within 90 days of discovering or acquiring a new significant financial interest. -Twice per year. -After they receive funding but before they start their research. -No later than the time of applying for funding.

-No later than the time of applying for funding.