PN NCLEX 6th Edition-Pharmacology/Oncology

A client with cancer has received a course of chemotherapy with fluorouracil (Adrucil). The nurse should plan to reinforce which instructions?

"Do not get any immunizations without health care provider approval."

Cyclophosphamide is prescribed for a client with a diagnosis of breast cancer. The nurse has reinforced instructions to the client regarding the medication to prevent hemorrhagic cystitis. Which statement by the client indicates an understanding of this chemotherapeutic regimen?

"I need to increase my fluid intake to 2000 to 3000 mL daily."

A client with breast cancer has been given a prescription for cyclophosphamide. The nurse determines that the client understands the proper use of the medication if the client makes which statement?

"I will increase fluid intake to 2 to 3 L/day."

The client with ovarian cancer is being treated with vincristine (Vincasar). The nurse monitors the client, knowing that which adverse effect is specific to this medication?

. Extremity numbness

A client with benign prostatic hyperplasia is being administered finasteride (Proscar). Which information should be included in the plan of care?

A pregnant caregiver should not be exposed to the crushed tablets of finasteride.

Exemestane (Aromasin) 25 mg orally daily is prescribed for a client with advanced breast cancer. When reinforcing instructions to the client about the medication, which time does the nurse tell the client to take the medication?

After a meal

Which information should the nurse provide to the client who will be receiving chemotherapy with doxorubicin (Adriamycin)? Select all that apply.

Alopecia can occur. Cardiotoxicity can occur. Urine and sweat may turn red. The medication is administered by the intravenous route. Promptly report any signs of bleeding to the health care provider.

A client with advanced ovarian cancer is being treated with paclitaxel (Taxol). The nurse monitors the client closely for which side effect of the medication?

Bradycardia

Tamoxifen (Soltamox) is prescribed for the client with metastatic breast carcinoma. The nurse understands that which is the primary action of this medication?

Compete with estradiol for binding to estrogen in tissues containing high concentrations of receptors.

Tamoxifen is prescribed for the client with metastatic breast carcinoma. The nurse assists in planning care, knowing that which is the primary action of this medication?

Compete with estradiol for binding to estrogen in tissues containing high concentrations of receptors.

Capecitabine (Xeloda) is prescribed for a client with metastatic breast cancer. The nurse reinforces information to the client about the medication including what frequent side effect?

Diarrhea

The nurse is caring for a child who is receiving chemotherapy for treatment of leukemia and prepares to address which expected needs of this client? Select all that apply.

Fatigue Easy bruising Possible infections

The nurse is caring for a client receiving chemotherapy and determines that the client has developed myelosuppression. Which laboratory value would support the client's diagnosis of myelosuppression?

Hemoglobin 9.4 g/dL, hematocrit 26%

The nurse tells a client with leukemia that allopurinol (Zyloprim) has been added to the medication list. The client is currently receiving busulfan (Myleran). When the client asks the purpose of the new medication, the nurse responds that allopurinol is intended to prevent which complication?

Hyperuricemia

The nurse is reinforcing medication instructions to a client with breast cancer who is receiving cyclophosphamide. Which instruction should the nurse provide to the client?

Increase fluid intake to 2000 to 3000 mL daily.

The nurse is analyzing the laboratory results of a client with leukemia who has received a regimen of chemotherapy. Which laboratory value should the nurse note as a result of the massive cell destruction that occurred from the chemotherapy?

Increased uric acid level

The nurse is caring for a client who is receiving an intravenous (IV) infusion of an antineoplastic medication. During the infusion, the client complains of pain at the insertion site. During an inspection of the site, the nurse notes redness and swelling. The nurse should take which appropriate action?

Notify the registered nurse.

The client with small cell lung cancer is being treated with etoposide (Toposar). The nurse assisting in caring for the client during its administration should understand that which side/adverse effect is specifically associated with this medication?

Orthostatic hypotension

A client is scheduled to receive chemotherapy with a group of medications, one of which is asparaginase (Elspar). The nurse anticipates that this medication will be removed from the regimen after noting which disorder in the client's medical record?

Pancreatitis

The nurse is reviewing the history and physical examination of a client who will be receiving asparaginase (Elspar), an antineoplastic agent. The nurse consults with the registered nurse regarding the administration of the medication if which is documented in the client's history?

Pancreatitis

The nurse is reviewing the laboratory results of a client receiving chemotherapy for cancer. The nurse reports which abnormal result to the health care provider?

Platelet count, 40,000 cells/mm3

A client with lung cancer is receiving a high dose of methotrexate (Rheumatrex). Leucovorin (citrovorum factor, folic acid) is also prescribed. The nurse who is assisting in planning care for the client understands that administering the leucovorin is for which purpose?

Preserve normal cells.

The nurse is assigned to care for a client with metastatic breast cancer who is taking tamoxifen citrate. The nurse monitors for which trends in laboratory values that should indicate an adverse effect?

The nurse is assigned to care for a client with metastatic breast cancer who is taking tamoxifen citrate. The nurse monitors for which trends in laboratory values that should indicate an adverse effect?

Anastrozole (Arimidex) is prescribed for a postmenopausal client with breast cancer. The nurse assists in developing a plan of care for the client and suggests monitoring the client closely for which adverse effect of this medication?

Thromboembolism

Megestrol acetate (Megace), an antineoplastic medication, is prescribed for the client with metastatic endometrial carcinoma. The nurse reviews the client's history and contacts the registered nurse if which diagnosis is documented in the client's history?

Thrombophlebitis

A client with cancer is receiving cisplatin. Which finding indicates that the client is experiencing an adverse effect of the medication?

Tinnitus

The nurse is assisting with caring for a client with cancer who is receiving cisplatin. Which adverse effects are associated with this medication? Select all that apply.

Tinnitus Ototoxicity Nephrotoxicity Hypomagnesemia

A client diagnosed with testicular cancer is prescribed cisplatin (Platinol-AQ). The nurse should monitor for which toxic effect of this medication?

Tinnuitis

The client with acute myelocytic leukemia is being treated with busulfan (Myleran). Which laboratory value should the nurse specifically monitor during treatment with this medication?

Uric acid level

A client with carcinoma of the breast is admitted to the hospital for treatment with intravenous vincristine (Oncovin). The client tells the nurse that she has been told by her friends that she is going to lose all her hair. The nurse makes which appropriate response to the client?

"Hair loss may occur, and it will grow back, but it may have a different color or texture."

The nurse is reinforcing information regarding chemotherapy with a client who has been diagnosed with cancer. The nurse tells the client that which is an advantage of continuous intravenous (IV) chemotherapy?

It uses smaller doses to kill cancer cells, so it is less toxic to normal tissues.

Letrozole (Femara) is prescribed for a postmenopausal client with advanced breast cancer. Which side effect of this medication should the nurse reinforce in the instructions to the client regarding this medication?

Leg pain

The client with metastatic breast cancer is receiving tamoxifen (Soltamox). The nurse specifically monitors which laboratory value while the client is taking this medication?

Calcium level

A client with breast cancer is being treated with cyclophosphamide. The nurse plans care, knowing that this medication fits which classification?

Cell cycle phase nonspecific

The licensed practical nurse (LPN) is assisting the registered nurse (RN) to create a teaching plan for the client receiving an antineoplastic medication. The LPN expects which information to be included?

Consult with health care providers (HCPs) before receiving immunizations.

The client with non-Hodgkin's lymphoma is receiving daunorubicin (DaunoXome). Which sign/symptom should indicate to the nurse that the client is experiencing a toxic effect related to the medication?

Crackles on auscultation of the lungs

A client with carcinoma is admitted to the hospital for a chemotherapy treatment with intravenous bleomycin sulfate. The plan of care mentions observing for interstitial pneumonitis as the priority of care. Which finding most closely correlates to symptoms of interstitial pneumonitis, requires reporting?

Lung wheezing and shortness of breath

The nurse is providing care for a client with a diagnosis of germ cell cancer of the testes who has been prescribed ifosfamide (Ifex). The nurse anticipates that the client will also be prescribed which additional antineoplastic medication?

Mesna (Mesnex)

A female client undergoing chemotherapy with intravenous vincristine sulfate (Oncovin) has been given information about the treatment. The nurse determines that the client has adequate understanding of the side effects of treatment if the client makes which statement about her hair?

My hair may be lost temporarily but may grow back with a different color and texture.

A client with cancer is receiving daunorubicin (Cerubidine) intravenously. The nurse assigned to assist in caring for the client monitors for which commonly expected side effect?

Nausea and vomiting

A client diagnosed with acute lymphocytic leukemia has been prescribed asparaginase (Elspar). Which finding represents possible medication toxicity?

Prolonged blood clotting times

The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for the client anticipates that which diagnostic study will be prescribed?

Pulmonary function studies

Docetaxel (Taxotere) is prescribed for a client with metastatic breast cancer. In addition, dexamethasone is prescribed to be administered before initiation of the docetaxel. What is the rationale for the addition of dexamethasone to the treatment plan that the nurse should explain to the client?

Reduces the severity of fluid retention

The nurse is helping prepare instructions for a client who has developed stomatitis following the administration of a course of antineoplastic medications. Which instruction does the nurse suggest to include in the plan of care?

Rinse the mouth with diluted baking soda or saline.

The nurse is caring for a client with a diagnosis of metastatic breast carcinoma. Tamoxifen citrate 10 mg orally twice daily is prescribed for the client, and the nurse is reinforcing instructions to the client regarding the medication. Which statement by the client would indicate an understanding of the medication?

"If I have difficulty seeing, I need to call the health care provider."

A client with bladder cancer is receiving cisplatin and vincristine (Oncovin). The nurse plans care, knowing that which is the purpose of administering both of these medications?

Decrease medication resistance and reduce medication toxicity.

A client with acute nonlymphocytic anemia receives treatment with cytarabine (ARA-C). The nurse reinforces medication instructions to the client and tells the client that it is important to report which adverse effect to the health care provider?

Sore throat