Aldol Lab Info

what further dehydration does under heat

produces an a,B-unsaturated carbonyl compound

what we do after everything is added

stir for 10 min or until solidifies

what to do if pressure indicator turns red

unscrew the press bc the anvil can crack

what we add second

3 drops of 50% OH

Why does the initial beta hydroxy ketone undergo rapid dehydration? 1. Because the dehydrated product is mores stable because it is a solid. 2. Because the dehydrated product is a lot more fun to say. 3. Becuase the dehydrated product is more stable due to the trans product. 4. Because the dehydrated product is more stable due to the extended conjugation.

4. Because the dehydrated product is more stable due to the extended conjugation.

what we do to eliminate multiple enolate possibilities

NaOH w/heat, LDA, only one carbonyl with a-proton

what we are adding

acetophenone and p-anisaldehyde

what we add first

add 0.2 mL p-anisaldehyde, 0.2 mL acetophenone, and 1 mL of ethanol to a 5 mL conical vial

the aldol reaction

addition reaction of an enol or enolate to a carbonyl compound

what using only one carbonyl compound that contains an a-proton does

avoids needing to make enolate separately

what you must do before using the GC

clean top plate with isopropanol allow air dry, inspect underside of press, turn press until halfway green

what the aldol reaction does

converts two carbonyl compounds into a B-hydroxy carbonyl compound