Ch 27.5

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Which of the following is the best way of describing respiratory compensation?

A change in the respiratory rate that helps stabilize the pH of the ECF.

Which of the following is not consistent with rising CO2 levels?

Additional Na+ ions are released.

Acid is a natural byproduct of many metabolic processes. Which of the following does not contribute to an increase in H+?

H+ is increased by expiration of CO2 by the lungs.

Which term is correctly matched up with its definition?

Salt—an ionic compound consisting of a cation other than hydrogen and an anion other than a hydroxide ion

What is the kidney's response to acidosis?

Secretion of H+ into urine

Which of the following is NOT a buffer system in the ECF or ICF?

Sulfate buffer system

Which of the following does not occur when the pH increases (become more basic)?

The carboxylate ion can act as a weak base and accept additional H+ ions.

What is required for the body to be in acid-base balance?

The production of hydrogen ions is exactly offset by their loss.

In a protein buffer system, if the pH increases, the carboxyl group (COOH) of the amino acid dissociates and releases __________.

a hydrogen ion

Deviations outside of the normal pH range due to increases in hydrogen ion concentrations would do all of the following except __________.

decrease the rate of respiration

The primary role of the carbonic acid−bicarbonate buffer system is to __________.

prevent changes in pH caused by metabolic and fixed acids in the ECF

The hemoglobin buffer system helps prevent drastic alterations in pH when __________.

the plasma PCO2 is rising or falling

Why must tubular fluid in the nephron be buffered?

to keep H+ from diffusing back into the blood. To prevent the pH of the urine from becoming too low. To allow secretion of H+ to continue

A pH below ____ or above _____ is not sustainable for life.

6.8; 7.7

What is the normal pH of ECF?

7.35-7.45

If the partial pressure of CO2 rises in the blood, which of the following happens?

A decrease in pH

Which of the following is not accurate regarding the generation of ammonia within kidney tubules?

Ammonia is broken down by carbonic anhydrase to form ammonium ions.

After a person consumes a meal, the levels of which ion rises in the blood in response to increased acid production in the stomach?

Bicarbonate

What is the term for a substance that opposes a change in pH in a solution and can either remove or replace hydrogen ions?

Buffer

Acidosis is a more common problem than alkalosis because many acids are the direct byproducts of metabolic reactions. Which of the following acids is not a metabolic acid?

Carbonic acid

Which of the following is a volatile acid and is a product of the combination of carbon dioxide and water?

Carbonic acid

Which buffer is the most important buffer in the extracellular fluid?

Carbonic acid-bicarbonate buffer

Severe acidosis (blood pH below 7.0) can be deadly for all of the following reasons except _______________.

hyperventilation leading to a lack of oxygen to critical tissues

Blood pH is normally between __________.

pH 7.35−7.45


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