Exam 2

Which of the following shows the correct changes in thermodynamic properties for a chemical reaction in which amino acids are linked to form a protein? A) +ΔH, +ΔS, +ΔG B) +ΔH, -ΔS, -ΔG C) +ΔH, -ΔS, +ΔG D) -ΔH, -ΔS, +ΔG E) -ΔH, +ΔS, +ΔG

+ΔH, -ΔS, +ΔG

During a laboratory experiment, you discover that an enzyme-catalyzed reaction has a ∆G of -20 kcal/mol. If you double the amount of enzyme in the reaction, what will be the ∆G for the new reaction? A) -40 kcal/mol B) -20 kcal/mol C) 0 kcal/mol D) +20 kcal/mol E) +40 kcal/mol

-20 kcal/mol

Substrate-level phosphorylation accounts for approximately what percentage of the ATP formed by the reactions of glycolysis? A) 0% B) 2% C) 10% D) 38% E) 100%

100%

Starting with one molecule of glucose, the energy-containing products of glycolysis are A) 2 NAD+, 2 pyruvate, and 2 ATP. B) 2 NADH, 2 pyruvate, and 2 ATP. C) 2 FADH2, 2 pyruvate, and 4 ATP. D) 6 CO2, 2 ATP, and 2 pyruvate. E) 6 CO2, 30 ATP, and 2 pyruvate.

2 NADH, 2 pyruvate, and 2 ATP.

Which of the following is the smallest closed system? A) a cell B) an organism C) an ecosystem D) Earth E) the universe

the universe

Which of the following statements describes enzyme cooperativity? A) A multienzyme complex contains all the enzymes of a metabolic pathway. B) A product of a pathway serves as a competitive inhibitor of an early enzyme in the pathway. C) A substrate molecule bound to an active site of one subunit promotes substrate binding to the active site of other subunits. D) Several substrate molecules can be catalyzed by the same enzyme. E) A substrate binds to an active site and inhibits cooperation between enzymes in a pathway.

A substrate molecule bound to an active site of one subunit promotes substrate binding to the active site of other subunits.

A number of systems for pumping ions across membranes are powered by ATP. Such ATP-powered pumps are often called ATPases although they don't often hydrolyze ATP unless they are simultaneously transporting ions. Because small increases in calcium ions in the cytosol can trigger a number of different intracellular reactions, cells keep the cytosolic calcium concentration quite low under normal conditions, using ATP-powered calcium pumps. For example, muscle cells transport calcium from the cytosol into the membranous system called the sarcoplasmic reticulum (SR). If a resting muscle cell's cytosol has a free calcium ion concentration of 10-7 while the concentration in the SR is 10-2, then how is the ATPase acting? A) ATPase activity must be powering an inflow of calcium from the outside of the cell into the SR. B) ATPase activity must be transferring i to the SR to enable this to occur. C) ATPase activity must be pumping calcium from the cytosol to the SR against the concentration gradient. D) ATPase activity must be opening a channel for the calcium ions to diffuse back into the SR along the concentration gradient. E) ATPase activity must be routing calcium ions from the SR to the cytosol, and then to the cell's environment.

ATPase activity must be pumping calcium from the cytosol to the SR against the concentration gradient.

Which of the following is true of the evolution of cell membranes? A) Cell membranes have stopped evolving now that they are fluid mosaics. B) Cell membranes cannot evolve if the membrane proteins do not. C) The evolution of cell membranes is driven by the evolution of glycoproteins and glycolipids. D) All components of membranes evolve in response to natural selection. E) An individual organism selects its preferred type of cell membrane for particular functions.

All components of membranes evolve in response to natural selection.

Living organisms increase in complexity as they grow, resulting in a decrease in the entropy of an organism. How does this relate to the second law of thermodynamics? A) Living organisms do not obey the second law of thermodynamics, which states that entropy must increase with time. B) Life obeys the second law of thermodynamics because the decrease in entropy as the organism grows is exactly balanced by an increase in the entropy of the universe. C) Living organisms do not follow the laws of thermodynamics. D) As a consequence of growing, organisms cause a greater increase in entropy in their environment than the decrease in entropy associated with their growth. E) Living organisms are able to transform energy into entropy.

As a consequence of growing, organisms cause a greater increase in entropy in their environment than the decrease in entropy associated with their growth.

Which of the following statements describes the results of this reaction? C6H12O6 + 6 O2 → 6 CO2 + 6 H2O + Energy A) C6H12O6 is oxidized and O2 is reduced. B) O2 is oxidized and H2O is reduced. C) CO2 is reduced and O2 is oxidized. D) C6H12O6 is reduced and CO2 is oxidized. E) O2 is reduced and CO2 is oxidized.

C6H12O6 is oxidized and O2 is reduced.

Which of the following would likely move through the lipid bilayer of a plasma membrane most rapidly? A) CO2 B) an amino acid C) glucose D) K+ E) starch

CO2

Why does the oxidation of organic compounds by molecular oxygen to produce CO2 and water release free energy? A) The covalent bonds in organic molecules and molecular oxygen have more kinetic energy than the covalent bonds in water and carbon dioxide. B) Electrons are being moved from atoms that have a lower affinity for electrons (such as C) to atoms with a higher affinity for electrons (such as O). C) The oxidation of organic compounds can be used to make ATP. D) The electrons have a higher potential energy when associated with water and CO2 than they do in organic compounds. E) The covalent bond in O2 is unstable and easily broken by electrons from organic molecules.

Electrons are being moved from atoms that have a lower affinity for electrons (such as C) to atoms with a higher affinity for electrons (such as O).

Which of the following is a statement of the first law of thermodynamics? A) Energy cannot be created or destroyed. B) The entropy of the universe is decreasing. C) The entropy of the universe is constant. D) Kinetic energy is stored energy that results from the specific arrangement of matter. E) Energy cannot be transferred or transformed.

Energy cannot be created or destroyed.

Which of the following statements regarding enzymes is true? A) Enzymes increase the rate of a reaction by making the reaction more exergonic. B) Enzymes increase the rate of a reaction by lowering the activation energy barrier. C) Enzymes increase the rate of a reaction by reducing the rate of reverse reactions. D) Enzymes change the equilibrium point of the reactions they catalyze. E) Enzymes make the rate of a reaction independent of substrate concentrations.

Enzymes increase the rate of a reaction by lowering the activation energy barrier.

Why is ATP an important molecule in metabolism? A) Its hydrolysis provides an input of free energy for exergonic reactions. B) It provides energy coupling between exergonic and endergonic reactions. C) Its terminal phosphate group contains a strong covalent bond that, when hydrolyzed, releases free energy. D) Its terminal phosphate bond has higher energy than the other two. E) It is one of the four building blocks for DNA synthesis.

It provides energy coupling between exergonic and endergonic reactions.

Which of the following statements is correct about diffusion? A) It is very rapid over long distances. B) It requires an expenditure of energy by the cell. C) It is a passive process in which molecules move from a region of higher concentration to a region of lower concentration. D) It is an active process in which molecules move from a region of lower concentration to one of higher concentration. E) It requires integral proteins in the cell membrane.

It is a passive process in which molecules move from a region of higher concentration to a region of lower concentration.

For the hydrolysis of ATP to ADP + i, the free energy change is -7.3 kcal/mol under standard conditions (1 M concentration of both reactants and products). In the cellular environment, however, the free energy change is about -13 kcal/mol. What can we conclude about the free energy change for the formation of ATP from ADP and i under cellular conditions? A) It is +7.3 kcal/mol. B) It is less than +7.3 kcal/mol. C) It is about +13 kcal/mol. D) It is greater than +13 kcal/mol. E) The information given is insufficient to deduce the free energy change.

It is about +13 kcal/mol.

When chemical, transport, or mechanical work is done by an organism, what happens to the heat generated? A) It is used to power yet more cellular work. B) It is used to store energy as more ATP. C) It is used to generate ADP from nucleotide precursors. D) It is lost to the environment. E) It is transported to specific organs such as the brain.

It is lost to the environment.

The sodium-potassium pump in animal cells requires cytoplasmic ATP to pump ions across the plasma membrane. When the proteins of the pump are first synthesized in the rough ER, what side of the ER membrane will the ATP binding site be on? A) It will be on the cytoplasmic side of the ER. B) It will be on the side facing the interior of the ER. C) It could be facing in either direction because proteins are properly reoriented in the Golgi apparatus. D) It doesn't matter, because the pump is not active in the ER.

It will be on the cytoplasmic side of the ER.

Which of the following is true of metabolism in its entirety in all organisms? A) Metabolism depends on a constant supply of energy from food. B) Metabolism depends on an organism's adequate hydration. C) Metabolism uses all of an organism's resources. D) Metabolism consists of all the energy transformation reactions in an organism. E) Metabolism manages the increase of entropy in an organism.

Metabolism consists of all the energy transformation reactions in an organism.

Which of the following statements describes NAD+? A) NAD+ is reduced to NADH during glycolysis, pyruvate oxidation, and the citric acid cycle. B) NAD+ has more chemical energy than NADH. C) NAD+ is oxidized by the action of hydrogenases. D) NAD+ can donate electrons for use in oxidative phosphorylation. E) In the absence of NAD+, glycolysis can still function.

NAD+ is reduced to NADH during glycolysis, pyruvate oxidation, and the citric acid cycle.

In addition to ATP, what are the end products of glycolysis? A) CO2 and H2O B) CO2 and pyruvate C) NADH and pyruvate D) CO2 and NADH E) H2O, FADH2, and citrate

NADH and pyruvate

Which of the following membrane activities require energy from ATP hydrolysis? A) facilitated diffusion of chloride ions across the membrane through a chloride channel B) movement of water into a cell C) Na+ ions moving out of a mammalian cell bathed in physiological saline D) movement of glucose molecules into a bacterial cell from a medium containing a higher concentration of glucose than inside the cell E) movement of carbon dioxide out of a paramecium

Na+ ions moving out of a mammalian cell bathed in physiological saline

Which of the following statements correctly describes the normal tonicity conditions for functioning plant and animal cells? A) The animal cell is in a hypotonic solution, and the plant cell is in an isotonic solution. B) The animal cell is in an isotonic solution, and the plant cell is in a hypertonic solution. C) The animal cell is in a hypertonic solution, and the plant cell is in an isotonic solution. D) The animal cell is in an isotonic solution, and the plant cell is in a hypotonic solution. E) The animal cell is in a hypertonic solution, and the plant cell is in a hypotonic solution.

The animal cell is in an isotonic solution, and the plant cell is in a hypotonic solution.

According to the induced fit hypothesis of enzyme catalysis, which of the following is correct? A) The binding of the substrate depends on the shape of the active site. B) Some enzymes change their structure when activators bind to the enzyme. C) A competitive inhibitor can outcompete the substrate for the active site. D) The binding of the substrate changes the shape of the enzyme's active site. E) The active site creates a microenvironment ideal for the reaction.

The binding of the substrate changes the shape of the enzyme's active site.

When a plant cell, such as one from a peony stem, is submerged in a very hypotonic solution, what is likely to occur? A) The cell will burst. B) The cell membrane will lyse. C) Plasmolysis will shrink the interior. D) The cell will become flaccid. E) The cell will become turgid.

The cell will become turgid.

Which of the following is a reasonable explanation for why unsaturated fatty acids help keep any membrane more fluid at lower temperatures? A) The double bonds form kinks in the fatty acid tails, preventing adjacent lipids from packing tightly. B) Unsaturated fatty acids have a higher cholesterol content and therefore more cholesterol in membranes. C) Unsaturated fatty acids are more polar than saturated fatty acids. D) The double bonds block interaction among the hydrophilic head groups of the lipids. E) The double bonds result in shorter fatty acid tails and thinner membranes.

The double bonds form kinks in the fatty acid tails, preventing adjacent lipids from packing tightly.

When electrons move closer to a more electronegative atom, what happens? A) The more electronegative atom is reduced, and energy is released. B) The more electronegative atom is reduced, and energy is consumed. C) The more electronegative atom is oxidized, and energy is consumed. D) The more electronegative atom is oxidized, and energy is released. E) The more electronegative atom is reduced, and entropy decreases.

The more electronegative atom is reduced, and energy is released.

In order for a protein to be an integral membrane protein it would have to be A) hydrophilic. B) hydrophobic. C) amphipathic, with at least one hydrophobic region. D) completely covered with phospholipids. E) exposed on only one surface of the membrane.

amphipathic, with at least one hydrophobic region.

A patient has had a serious accident and lost a lot of blood. In an attempt to replenish body fluids, distilled water-equal to the volume of blood lost-is transferred directly into one of his veins. What will be the most probable result of this transfusion? A) It will have no unfavorable effect as long as the water is free of viruses and bacteria. B) The patient's red blood cells will shrivel up because the blood fluid has become hypotonic compared to the cells. C) The patient's red blood cells will swell because the blood fluid has become hypotonic compared to the cells. D) The patient's red blood cells will shrivel up because the blood fluid has become hypertonic compared to the cells. E) The patient's red blood cells will burst because the blood fluid has become hypertonic compared to the cells.

The patient's red blood cells will swell because the blood fluid has become hypotonic compared to the cells.

Which of the following statements is true about enzyme-catalyzed reactions? A) The reaction is faster than the same reaction in the absence of the enzyme. B) The free energy change of the reaction is opposite from the reaction that occurs in the absence of the enzyme. C) The reaction always goes in the direction toward chemical equilibrium. D) Enzyme-catalyzed reactions require energy to activate the enzyme. E) Enzyme-catalyzed reactions release more free energy than noncatalyzed reactions.

The reaction is faster than the same reaction in the absence of the enzyme.

Which of the following is true for all exergonic reactions? A) The products have more total energy than the reactants. B) The reaction proceeds with a net release of free energy. C) The reaction goes only in a forward direction: all reactants will be converted to products, but no products will be converted to reactants. D) A net input of energy from the surroundings is required for the reactions to proceed. E) The reactions are rapid.

The reaction proceeds with a net release of free energy.

Cell membranes are asymmetrical. Which of the following is the most likely explanation? A) The cell membrane forms a border between one cell and another in tightly packed tissues such as epithelium. B) Cell membranes communicate signals from one organism to another. C) The two sides of a cell membrane face different environments and carry out different functions. D) The "innerness" and "outerness" of membrane surfaces are predetermined by genes. E) Proteins can only be associated with the cell membranes on the cytoplasmic side.

The two sides of a cell membrane face different environments and carry out different functions.

What is the difference (if any) between the structure of ATP and the structure of the precursor of the A nucleotide in RNA? A) The sugar molecule is different. B) The nitrogen-containing base is different. C) The number of phosphates is three instead of one. D) The number of phosphates is three instead of two. E) There is no difference.

There is no difference.

According to the fluid mosaic model of cell membranes, which of the following is a true statement about membrane phospholipids? A) They can move laterally along the plane of the membrane. B) They frequently flip-flop from one side of the membrane to the other. C) They occur in an uninterrupted bilayer, with membrane proteins restricted to the surface of the membrane. D) They are free to depart from the membrane and dissolve in the surrounding solution. E) They have hydrophilic tails in the interior of the membrane.

They can move laterally along the plane of the membrane.

Why are carbohydrates and fats considered high energy foods? A) They have a lot of oxygen atoms. B) They have no nitrogen in their makeup. C) They can have very long carbon skeletons. D) They have a lot of electrons associated with hydrogen. E) They are easily reduced.

They have a lot of electrons associated with hydrogen.

Which of the following statements is true concerning catabolic pathways? A) They combine molecules into more energy-rich molecules. B) They supply energy, primarily in the form of ATP, for the cell's work. C) They are endergonic. D) They are spontaneous and do not need enzyme catalysis. E) They build up complex molecules such as protein from simpler compounds.

They supply energy, primarily in the form of ATP, for the cell's work.

Mammalian blood contains the equivalent of 0.15 M NaCl. Seawater contains the equivalent of 0.45 M NaCl. What will happen if red blood cells are transferred to seawater? A) Water will leave the cells, causing them to shrivel and collapse. B) NaCl will be exported from the red blood cells by facilitated diffusion. C) The blood cells will take up water, swell, and eventually burst. D) NaCl will passively diffuse into the red blood cells. E) The blood cells will expend ATP for active transport of NaCl into the cytoplasm.

Water will leave the cells, causing them to shrivel and collapse.

The cell membranes of Antarctic ice fish might have which of the following adaptations? A) very long chain fatty acids B) branched isoprenoid lipids C) a high percentage of polyunsaturated fatty acids D) a higher percentage of trans-fatty acids E) no cholesterol

a high percentage of polyunsaturated fatty acids

Which of the following is an example of potential rather than kinetic energy? A) the muscle contractions of a person mowing grass B) water rushing over Niagara Falls C) light flashes emitted by a firefly D) a molecule of glucose E) the flight of an insect foraging for food

a molecule of glucose

Which of the following would increase the electrochemical potential across a membrane? A) a chloride channel B) a sucrose-proton cotransporter C) a proton pump D) a potassium channel E) both a proton pump and a potassium channel

a proton pump

The oxygen consumed during cellular respiration is involved directly in which process or event? A) glycolysis B) accepting electrons at the end of the electron transport chain C) the citric acid cycle D) the oxidation of pyruvate to acetyl CoA E) the phosphorylation of ADP to form ATP

accepting electrons at the end of the electron transport chain

Which of the following intermediary metabolites enters the citric acid cycle and is formed, in part, by the removal of a carbon (CO2) from one molecule of pyruvate? A) lactate B) glyceraldehydes-3-phosphate C) oxaloacetate D) acetyl CoA E) citrate

acetyl CoA

The transport of pyruvate into mitochondria depends on the proton-motive force across the inner mitochondrial membrane. How does pyruvate enter the mitochondrion? A) active transport B) diffusion C) facilitated diffusion D) through a channel E) through a pore

active transport

Which term most precisely describes the cellular process of breaking down large molecules into smaller ones? A) catalysis B) metabolism C) anabolism D) dehydration E) catabolism

catabolism

Which kind of metabolic poison would most directly interfere with glycolysis? A) an agent that reacts with oxygen and depletes its concentration in the cell B) an agent that binds to pyruvate and inactivates it C) an agent that closely mimics the structure of glucose but is not metabolized D) an agent that reacts with NADH and oxidizes it to NAD+ E) an agent that blocks the passage of electrons along the electron transport chain

an agent that closely mimics the structure of glucose but is not metabolized

The movement of potassium into an animal cell requires A) low cellular concentrations of sodium. B) high cellular concentrations of potassium. C) an energy source such as ATP. D) a cotransport protein. E) a potassium channel protein.

an energy source such as ATP.

Allosteric enzyme regulation is usually associated with A) lack of cooperativity. B) feedback inhibition. C) activating activity. D) an enzyme with more than one subunit. E) the need for cofactors.

an enzyme with more than one subunit.

Which of the following types of reactions would decrease the entropy within a cell? A) anabolic reactions B) hydrolysis C) respiration D) digestion E) catabolic reactions

anabolic reactions

How does a noncompetitive inhibitor decrease the rate of an enzyme reaction? A) by binding at the active site of the enzyme B) by changing the shape of the enzyme's active site C) by changing the free energy change of the reaction D) by acting as a coenzyme for the reaction E) by decreasing the activation energy of the reaction

by changing the shape of the enzyme's active site

How might an amino acid change at a site distant from the active site of the enzyme alter the enzyme's substrate specificity? A) by changing the enzyme's stability B) by changing the enzyme's location in the cell C) by changing the shape of the protein D) by changing the enzyme's pH optimum E) an amino acid change away from the active site cannot alter the enzyme's substrate specificity

by changing the shape of the protein

Which of the following is one of the ways that the membranes of winter wheat are able to remain fluid when it is extremely cold? A) by increasing the percentage of unsaturated phospholipids in the membrane B) by increasing the percentage of cholesterol molecules in the membrane C) by decreasing the number of hydrophobic proteins in the membrane D) by cotransport of glucose and hydrogen E) by using active transport

by increasing the percentage of unsaturated phospholipids in the membrane

) In a paramecium, cell surface integral membrane proteins are synthesized A) in the cytoplasm by free ribosomes. B) by ribosomes in the nucleus. C) by ribosomes bound to the rough endoplasmic reticulum. D) by ribosomes in the Golgi vesicles. E) by ribosomes bound to the inner surface of the plasma membrane

by ribosomes bound to the rough endoplasmic reticulum.

A system at chemical equilibrium A) consumes energy at a steady rate. B) releases energy at a steady rate. C) consumes or releases energy, depending on whether it is exergonic or endergonic. D) has zero kinetic energy. E) can do no work.

can do no work.

What is the term for metabolic pathways that release stored energy by breaking down complex molecules? A) anabolic pathways B) catabolic pathways C) fermentation pathways D) thermodynamic pathways E) bioenergetic pathways

catabolic pathways

In which of the following would there be the greatest need for osmoregulation? A) an animal connective tissue cell bathed in isotonic body fluid B) cells of a tidepool animal such as an anemone C) a red blood cell surrounded by plasma D) a lymphocyte before it has been taken back into lymph fluid E) a plant being grown hydroponically (in a watery mixture of designated nutrients)

cells of a tidepool animal such as an anemone

When you have a severe fever, what grave consequence may occur if the fever is not controlled? A) destruction of your enzymes' primary structure B) removal of amine groups from your proteins C) change in the tertiary structure of your enzymes D) removal of the amino acids in active sites of your enzymes E) binding of your enzymes to inappropriate substrates

change in the tertiary structure of your enzymes

Zinc, an essential trace element for most organisms, is present in the active site of the enzyme carboxypeptidase. The zinc most likely functions as a(n) A) competitive inhibitor of the enzyme. B) noncompetitive inhibitor of the enzyme. C) allosteric activator of the enzyme. D) cofactor necessary for enzyme activity. E) coenzyme derived from a vitamin.

cofactor necessary for enzyme activity.

The sodium-potassium pump is called an electrogenic pump because it A) pumps equal quantities of Na+ and K+ across the membrane. B) pumps hydrogen ions out of the cell. C) contributes to the membrane potential. D) ionizes sodium and potassium atoms. E) is used to drive the transport of other molecules against a concentration gradient.

contributes to the membrane potential.

The phosphate transport system in bacteria imports phosphate into the cell even when the concentration of phosphate outside the cell is much lower than the cytoplasmic phosphate concentration. Phosphate import depends on a pH gradient across the membrane-more acidic outside the cell than inside the cell. Phosphate transport is an example of A) passive diffusion. B) facilitated diffusion. C) active transport. D) osmosis. E) cotransport.

cotransport.

Where does glycolysis take place in eukaryotic cells? A) mitochondrial matrix B) mitochondrial outer membrane C) mitochondrial inner membrane D) mitochondrial intermembrane space E) cytosol

cytosol

Ions diffuse across membranes through specific ion channels A) down their chemical gradients. B) down their concentration gradients. C) down the electrical gradients. D) down their electrochemical gradients. E) down the osmotic potential gradients.

down their electrochemical gradients.

The presence of cholesterol in the plasma membranes of some animals A) enables the membrane to stay fluid more easily when cell temperature drops. B) enables the animal to remove hydrogen atoms from saturated phospholipids. C) enables the animal to add hydrogen atoms to unsaturated phospholipids. D) makes the membrane less flexible, allowing it to sustain greater pressure from within the cell. E) makes the animal more susceptible to circulatory disorders.

enables the membrane to stay fluid more easily when cell temperature drops.

A chemical reaction that has a positive ΔG is correctly described as A) endergonic. B) endothermic. C) enthalpic. D) spontaneous. E) exothermic.

endergonic.

The mechanism in which the end product of a metabolic pathway inhibits an earlier step in the pathway is most precisely described as A) metabolic inhibition. B) feedback inhibition. C) allosteric inhibition. D) noncooperative inhibition. E) reversible inhibition.

feedback inhibition.

During aerobic respiration, electrons travel downhill in which sequence? A) food → citric acid cycle → ATP → NAD+ B) food → NADH → electron transport chain → oxygen C) glucose → pyruvate → ATP → oxygen D) glucose → ATP → electron transport chain → NADH E) food → glycolysis → citric acid cycle → NADH → ATP

food → NADH → electron transport chain → oxygen

Which process in eukaryotic cells will proceed normally whether oxygen (O2) is present or absent? A) electron transport B) glycolysis C) the citric acid cycle D) oxidative phosphorylation E) chemiosmosis

glycolysis

A molecule that is phosphorylated A) has been reduced as a result of a redox reaction involving the loss of an inorganic phosphate. B) has a decreased chemical reactivity; it is less likely to provide energy for cellular work. C) has been oxidized as a result of a redox reaction involving the gain of an inorganic phosphate. D) has an increased chemical potential energy; it is primed to do cellular work. E) has less energy than before its phosphorylation and therefore less energy for cellular work.

has an increased chemical potential energy; it is primed to do cellular work.

Which of the following is (are) true for anabolic pathways? A) They do not depend on enzymes. B) They are usually highly spontaneous chemical reactions. C) They consume energy to build up polymers from monomers. D) They release energy as they degrade polymers to monomers. E) They consume energy to decrease the entropy of the organism and its environment.

hey consume energy to build up polymers from monomers.

An electron loses potential energy when it A) shifts to a less electronegative atom. B) shifts to a more electronegative atom. C) increases its kinetic energy. D) increases its activity as an oxidizing agent. E) moves further away from the nucleus of the atom.

shifts to a more electronegative atom.

Celery stalks that are immersed in fresh water for several hours become stiff and hard. Similar stalks left in a 0.15 M salt solution become limp and soft. From this we can deduce that the cells of the celery stalks are A) hypotonic to both fresh water and the salt solution. B) hypertonic to both fresh water and the salt solution. C) hypertonic to fresh water but hypotonic to the salt solution. D) hypotonic to fresh water but hypertonic to the salt solution. E) isotonic with fresh water but hypotonic to the salt solution.

hypertonic to fresh water but hypotonic to the salt solution.

Some of the drugs used to treat HIV patients are competitive inhibitors of the HIV reverse transcriptase enzyme. Unfortunately, the high mutation rate of HIV means that the virus rapidly acquires mutations with amino acid changes that make them resistant to these competitive inhibitors. Where in the reverse transcriptase enzyme would such amino acid changes most likely occur in drug-resistant viruses? A) in or near the active site B) at an allosteric site C) at a cofactor binding site D) in regions of the protein that determine packaging into the virus capsid E) such mutations could occur anywhere with equal probability

in or near the active site

When a membrane is freeze-fractured, the bilayer splits down the middle between the two layers of phospholipids. In an electron micrograph of a freeze-fractured membrane, the bumps seen on the fractured surface of the membrane are A) peripheral proteins. B) phospholipids. C) carbohydrates. D) integral proteins. E) cholesterol molecules.

integral proteins.

The active site of an enzyme is the region that A) binds allosteric regulators of the enzyme. B) is involved in the catalytic reaction of the enzyme. C) binds noncompetitive inhibitors of the enzyme. D) is inhibited by the presence of a coenzyme or a cofactor.

is involved in the catalytic reaction of the enzyme.

Water passes quickly through cell membranes because A) the bilayer is hydrophilic. B) it moves through hydrophobic channels. C) water movement is tied to ATP hydrolysis. D) it is a small, polar, charged molecule. E) it moves through aquaporins in the membrane.

it moves through aquaporins in the membrane.

Besides turning enzymes on or off, what other means does a cell use to control enzymatic activity? A) cessation of cellular protein synthesis B) localization of enzymes into specific organelles or membranes C) exporting enzymes out of the cell D) connecting enzymes into large aggregates E) hydrophobic interactions

localization of enzymes into specific organelles or membranes

The molecule that functions as the reducing agent (electron donor) in a redox or oxidation-reduction reaction A) gains electrons and gains potential energy. B) loses electrons and loses potential energy. C) gains electrons and loses potential energy. D) loses electrons and gains potential energy. E) neither gains nor loses electrons, but gains or loses potential energy.

loses electrons and loses potential energy.

A bacterium engulfed by a white blood cell through phagocytosis will be digested by enzymes contained in A) peroxisomes. B) lysosomes. C) Golgi vesicles. D) vacuoles. E) secretory vesicles.

lysosomes.

What is the voltage across a membrane called? A) water potential B) chemical gradient C) membrane potential D) osmotic potential E) electrochemical gradient

membrane potential

Singer and Nicolson's fluid mosaic model of the membrane proposed that A) membranes are a phospholipid bilayer. B) membranes are a phospholipid bilayer between two layers of hydrophilic proteins. C) membranes are a single layer of phospholipids and proteins. D) membranes consist of protein molecules embedded in a fluid bilayer of phospholipids. E) membranes consist of a mosaic of polysaccharides and proteins.

membranes consist of protein molecules embedded in a fluid bilayer of phospholipids.

Where are the proteins of the electron transport chain located? A) cytosol B) mitochondrial outer membrane C) mitochondrial inner membrane D) mitochondrial intermembrane space E) mitochondrial matrix

mitochondrial inner membrane

During cellular respiration, acetyl CoA accumulates in which location? A) cytosol B) mitochondrial outer membrane C) mitochondrial inner membrane D) mitochondrial intermembrane space E) mitochondrial matrix

mitochondrial matrix

Carbon dioxide (CO2) is released during which of the following stages of cellular respiration? A) glycolysis and the oxidation of pyruvate to acetyl CoA B) oxidation of pyruvate to acetyl CoA and the citric acid cycle C) the citric acid cycle and oxidative phosphorylation D) oxidative phosphorylation and fermentation E) fermentation and glycolysis

oxidation of pyruvate to acetyl CoA and the citric acid cycle

Which of these are not embedded in the hydrophobic portion of the lipid bilayer at all? A) transmembrane proteins B) integral proteins C) peripheral proteins D) integrins E) glycoproteins

peripheral proteins

White blood cells engulf bacteria through what process? A) exocytosis B) phagocytosis C) pinocytosis D) osmosis E) receptor-mediated exocytosis

phagocytosis

An organism with a cell wall would most likely be unable to take in materials through A) diffusion. B) osmosis. C) active transport. D) phagocytosis. E) facilitated diffusion.

phagocytosis.

Which of the following types of molecules are the major structural components of the cell membrane? A) phospholipids and cellulose B) nucleic acids and proteins C) phospholipids and proteins D) proteins and cellulose E) glycoproteins and cholesterol

phospholipids and proteins

The difference between pinocytosis and receptor-mediated endocytosis is that A) pinocytosis brings only water molecules into the cell, but receptor-mediated endocytosis brings in other molecules as well. B) pinocytosis increases the surface area of the plasma membrane whereas receptor-mediated endocytosis decreases the plasma membrane surface area. C) pinocytosis is nonselective in the molecules it brings into the cell, whereas receptor-mediated endocytosis offers more selectivity. D) pinocytosis requires cellular energy, but receptor-mediated endocytosis does not. E) pinocytosis can concentrate substances from the extracellular fluid, but receptor-mediated endocytosis cannot.

pinocytosis is nonselective in the molecules it brings into the cell, whereas receptor-mediated endocytosis offers more selectivity.

During glycolysis, when each molecule of glucose is catabolized to two molecules of pyruvate, most of the potential energy contained in glucose is A) transferred to ADP, forming ATP. B) transferred directly to ATP. C) retained in the two pyruvates. D) stored in the NADH produced. E) used to phosphorylate fructose to form fructose 6-phosphate.

retained in the two pyruvates.

You are working on a team that is designing a new drug. In order for this drug to work, it must enter the cytoplasm of specific target cells. Which of the following would be a factor that determines whether the molecule selectively enters the target cells? A) blood or tissue type of the patient B) hydrophobicity of the drug molecule C) lack of charge on the drug molecule D) similarity of the drug molecule to other molecules transported by the target cells E) lipid composition of the target cells' plasma membrane

similarity of the drug molecule to other molecules transported by the target cells

What kinds of molecules pass through a cell membrane most easily? A) large and hydrophobic B) small and hydrophobic C) large polar D) ionic E) monosaccharides such as glucose

small and hydrophobic

The ATP made during glycolysis is generated by A) substrate-level phosphorylation. B) electron transport. C) photophosphorylation. D) chemiosmosis. E) oxidation of NADH to NAD+.

substrate-level phosphorylation.

A solution of starch at room temperature does not readily decompose to form a solution of simple sugars because A) the starch solution has less free energy than the sugar solution. B) the hydrolysis of starch to sugar is endergonic. C) the activation energy barrier for this reaction cannot be surmounted. D) starch cannot be hydrolyzed in the presence of so much water. E) starch hydrolysis is nonspontaneous.

the activation energy barrier for this reaction cannot be surmounted.

Protein kinases are enzymes that catalyze phosphorylation of target proteins at specific sites, whereas protein phosphatases catalyze removal of phosphate(s) from phosphorylated proteins. Phosphorylation and dephosphorylation can function as an on-off switch for a protein's activity, most likely through A) the change in a protein's charge leading to a conformational change. B) the change in a protein's charge leading to cleavage. C) a change in the optimal pH at which a reaction will occur. D) a change in the optimal temperature at which a reaction will occur. E) the excision of one or more peptides.

the change in a protein's charge leading to a conformational change.

Which of the following best describes enthalpy (H)? A) the total kinetic energy of a system B) the heat content of a chemical system C) the system's entropy D) the cell's energy equilibrium E) the condition of a cell that is not able to react

the heat content of a chemical system

When biological membranes are frozen and then fractured, they tend to break along the middle of the bilayer. The best explanation for this is that A) the integral membrane proteins are not strong enough to hold the bilayer together. B) water that is present in the middle of the bilayer freezes and is easily fractured. C) hydrophilic interactions between the opposite membrane surfaces are destroyed on freezing. D) the carbon-carbon bonds of the phospholipid tails are easily broken. E) the hydrophobic interactions that hold the membrane together are weakest at this point.

the hydrophobic interactions that hold the membrane together are weakest at this point.

The primary function of polysaccharides attached to the glycoproteins and glycolipids of animal cell membranes is A) to facilitate diffusion of molecules down their concentration gradients. B) to actively transport molecules against their concentration gradients. C) to maintain the integrity of a fluid mosaic membrane. D) to maintain membrane fluidity at low temperatures. E) to mediate cell-to-cell recognition.

to mediate cell-to-cell recognition.

How many carbon atoms are fed into the citric acid cycle as a result of the oxidation of one molecule of pyruvate? A) two B) four C) six D) eight E) ten

two

In glycolysis, for each molecule of glucose oxidized to pyruvate A) two molecules of ATP are used and two molecules of ATP are produced. B) two molecules of ATP are used and four molecules of ATP are produced. C) four molecules of ATP are used and two molecules of ATP are produced. D) two molecules of ATP are used and six molecules of ATP are produced. E) six molecules of ATP are used and six molecules of ATP are produced.

two molecules of ATP are used and four molecules of ATP are produced.

The mathematical expression for the change in free energy of a system is ΔG =ΔH - TΔS. Which of the following is (are) correct? A) ΔS is the change in enthalpy, a measure of randomness. B) ΔH is the change in entropy, the energy available to do work. C) ΔG is the change in free energy. D) T is the temperature in degrees Celsius.

ΔG is the change in free energy.