Medicinal Chemistry Exam 2 Review
1:100 [A-]/[HA]
Aspirin has a pKa of 3.4. What is the ratio of A¯ to HA in the stomach (pH = 1.4)?
acidic
Acid, Neutral, Basic, or Zwitterionic?
2.3
Given the hydrogen ion concentration of a drug molecule as 0.005M, calculate the pH. (Round to 1 decimal place)
can not be determined (neutral molecule)
If the pKa ofthis drug is 8.69 with a pH of 7.4, What is the percent unionized?
Aldehyde
What functional group is formed when a primary alcohol is oxidized?
basic
Acid, Neutral, Basic, or Zwitterionic?
neutral
Acid, Neutral, Basic, or Zwitterionic?
zwitterionic
Acid, Neutral, Basic, or Zwitterionic?
acidic
Acidic, Neutral, Basic, or Zwitterionic?
10000:1 [A-]/[HA]
Aspirin has a pKa of 3.4. What is the ratio of A¯ to HA in the blood (pH = 7.4)?
6.5
Calculate the pH required for Ligma [HA] to be 40% if the pKa is 6.3. (Round to one decimal point)
5
Fifty percent of a weak acid is in an ionized form in a solution with pH of 5.000, what is the pKa value for the weak acid?
0.3
Given the hydrogen ion concentration of a drug molecule as 0.5M, calculate the pH. (Round to 1 decimal place)
Not enough information to solve
If the pKa of this drug is 4.72 with percent ionization of 43%, what is the pH of the drug? (Round to one decimal point)
74.3%
If the pKa of this drug is 8.56 with a hydrogen ion concentration of 8e-9 M, what is the percent ionization? (Round to one decimal point)
basic
What type of drug would be used along with a inorganic acid to produce a inorganic salt?
basic
What type of drug would be used along with a organic acid to produce a organic salt?
acidic
What type of drug would be used along with a organic base to produce a organic salt?
acidic
what type of drug would be used along with a inorganic base to produce a inorganic salt?