MLT 201 Lecture Quiz 3 Book Chs. 6-7 Questions

The first commercial centrifugal analyzer was introduced in what year? a) 1970 b) 1957 c) 1967 d) 1976

1970

Which of the following approaches to the analyzer automation can use mixing paddles to stir? a) Discrete analysis b) Centrifugal analysis c) Continuous flow d) Dry chemistry slide analysis

Discrete analysis

Which of the following types of analyzers offers random-access capabilities? a) Discrete analyzers b) Continuous-flow analyzers c) Centrifugal analyzers d) None of these

Discrete analyzers

PCR/ESI-TOF has the distinct advantage in pathogen identification because: a) Requires the patient sample to be cultured and then analysis can be performed. b) It can be used directly from patient specimens. c) Uses the protein "finger print" to identify the pathogen.

It can be used directly from patient specimens

Modifications in microsampling and reagent dispensing improve which of the following phases in clinical testing? a) Physician ordering phase b) Preanalytical phase c) Analytical phase d) Post analytical phase e) All of the above

Analytical phase

An example of a modular integrated chemistry/immunoassay analyzer would be the: a) Aeroset b) Dimension Vista 3000T c) Paramax d) Vitros

Dimension Vista 3000T

In which of the following components of a chromatography instrument does selective separation of a mixture occur? a) Sample injection port b) Column c) Spectrometer d) Quadrupole e) Mass analyzer

Column

All of the following are advantages to automation EXCEPT a) Correction for deficiencies inherent in methodologies b) Increased number of tests performed c) Minimized labor component d) Use of small amounts of samples and reagents in comparison to manual procedures

Correction for deficiencies inherent in methodologies

In high-performance thin-layer chromatography (HPTLC), developed bands are compared with reference standard concentrations. Each band is measured by: a) Mass spectrometer b) Densitometer c) Ruler d) Buiret protein assay e) Two-dimensional electrophoresis

Densitometer

True or False? In chromatography, the stationary phase is always of a solid matrix.

False

Drugs of abuse are typically measured by: a) Thin-layer chromatography b) Liquid/liquid chromatography c) Gas/liquid chromatography d) Steric exclusion chromatography e) HPLC

Gas/liquid chromatography

All of the following are primary considerations in the selection of an automated chemistry analyzer EXCEPT: a) How reagents are added or mixed b) The cost of consumables c) Total instrument cost d) The labor component

How reagents are added or mixed

Which of the following is NOT a driving force for more automation? a) Increased use of chemistry panels b) High-volume testing c) Fast turnaround time d) Expectation of high-quality, accurate results

Increased use of chemistry panels

Mass spectrometry identifies analytes based on: a) Mass to charge ratio b) Retention factor c) Density of the band d) Molecular weight e) Solubility in the mobile phase

Mass to charge ratio

Which of the following statements is true? a) Partition chromatography is most appropriate to identifying analytes that may be distributed between two liquid phases. b) Steric exclusion chromatography is best-suited for separating analytes based on their solubility in the mobile solvent. c) In liquid-solid chromatography, the stationary phase separates analytes based on size, shape, and polarity. d) Ion-exchange chromatography has a resin phase that is soluble to water and separation of the mixture is based on magnitude and charge of ionic species. e) The partition coefficient is measured and compared with standards in thin layer chromatography.

Partition chromatography is most appropriate to identifying analytes that may be distributed between two liquid phases.

Bidirectional communication between the chemistry analyzer and the laboratory information system has had the greatest impact on which of the following phases of clinical testing? a) Preanalytical b) Analytical c) Postanalytical d) All of the above e) None of the above

Postanalytical

Which of the following steps in automation generally remains a manual process in most laboratories? a) Preparation of the sample b) Specimen measurement and delivery c) Reagent delivery d) Chemical reaction phase

Preparation of the sample

Dwell time refers to the: a) Time between initiation of a text and the completion of the analysis b) Number of tests an instrument can handle in a specific time c) Ability of an instrument to perform a defined workload in a specific time d) None of these

Time between initiation of a text and the completion of the analysis

Reflectance spectrometry uses which of the following? a) Luminometer b) Tungsten-halogen lamp c) Photomultiplier tube d) UV lamp e) Thermometer to monitor temperature in reaction vessel

Tungsten-halogen lamp

Which of the following chemistry analyzers uses slides to contain the entire reagent system? a) Vitros analyzers b) ACA analyzers c) Synchron analyzers d) None of these

Vitros analyzers