ATI Pharmacology Tetracycline
side effects of tetracycline
-GI upset -tooth discoloration in children and fetuses -hepatotoxicity -photosensitivity -superinfection (CDIFF, yeast infection)
indications for tetracycline
-bacterial infections -acne -lyme disease
key points for gentamicin
-monitor patients for tinnitus and hearing loss -monitor kidney function (creatinine levels, I&Os, observe urine for hematuria) -administer IM or IV -monitor peak/trough blood levels
side effects of gentamicin
-ototoxicity -nephrotoxicity -vertigo -ataxia
A nurse is caring for a client who has subacute bacterial endocarditis and is receiving antibiotics, including streptomycin IM. For which of the following manifestations should the nurse monitor as an adverse effect of this medication? A. Extremity paresthesias B. Urinary retention C. Severe constipation D. Complex partial seizures
A. Extremity paresthesias
A nurse is caring for a client who is starting a course of gentamicin IV for a serious respiratory infection. For which of the following manifestations should the nurse monitor as an adverse effect of this medication? (Select all that apply.) A. Pruitus B. Hematuria C. Muscle weakness D. Difficulty swallowing E. Vertigo
A. Pruitus B. Hematuria C. Muscle weakness E. Vertigo
A nurse is teaching a client about taking tetracyclines to treat a GI infection due to Helicobacter pylori. Which of the following statements should the nurse identify as an indication that the client understands the instructions? A. "I will take this medication with 8 oz of milk." B. "I will let my doctor know if I start having diarrhea." C. "I can stop taking this medication when I feel completely well." D. "I can take this medication just before bedtime."
B. "I will let my doctor know if I start having diarrhea."
A nurse is administering gentamicin by IV infusion at 0900. The medication will take 1 hr to infuse. When should the nurse plan to obtain a blood sample for a peak serum level of gentamicin? A. 1000 B. 1030 C. 11000 D. 1130
B. 1030
A nurse is caring for a client who is undergoing preparation for extensive colorectal surgery. Which of the following oral antibiotics should the nurse expect to administer specifically to suppress normal flora in the GI tract? A. Kanamycin B. Gentamicin C. Neomycin D. Tobramycin
C. Neomycin
examples of aminoglycosides
Gentamicin Tobramycin Amikacin
examples of tetracyclines
Tetracycline Doxycycline
mode of action of gentamicin
destroys bacteria by inhibiting protein synthesis
mode of action of tetracycline
prevents protein synthesis, inhibiting bacterial growth
indications for gentamicin
serious bacterial infections
