Neuro Pharm

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The patient who requires the LEAST cautionary measures when treated with carbidopa/levodopa (Sinemet) is:

- 43-year-old woman with hypothyroidism

After initiation of 300 mg serum phenytoin (Dilantin), daily levels should be check approximately:

- 7 days

To be of greatest benefit, corticosteroids in the treatment of Bell's palsy should be initiated within:

- 72 hours of symptom onset

Donepezil (Aricept), a cholinesterase inhibitor, is indicated in the treatment of:

- Alzheiner's Type dementia

The brand name of phenytoin sodium is:

- Dilantin

The generic name for Depakote is:

- Divalproex sodium

Which of the following medications is NOT a serotonin 5-HT1 receptor agonist?

- Fioricet

Which medication may be beneficial in the treatment of restless leg syndrome (RLS)?

- Gabapentin (Neurontin)

The brand name for levetiracetam is:

- Keppra

Which of the following medications is an N-methyl-D-aspartate receptor antagonist for the treatment of dementia of the Alzheimer's type?

- Memantine (Namenda)

Amantadine, an antiviral agent and an N-methyl-D-aspartate (NMDA) receptor antagonist, is indicated in the treatment of:

- Parkinsonism

The brand name for carbamazepine is:

- Tegretol

Which medication is approved for prophylactic treatment of migraine headaches?

- Topiramate (Topamax)

The brand name of oxcarbazepine is:

- Trileptal

Divalproex sodium (Depakote) for the treatment of epilepsy can be safely administered to:

- a 33-year-old woman with partial epilepsy who is breastfeeding

Medications with significant anticholinergic properties, such as amatadine (Symmetrel) to treat Parkinson's disease, block which neurotransmitter?

- acetylcholine

A medication used in a patient with a transient ischemic attack to prevent platelet aggregation and produce an anti-inflammatory effect in vessels by inhibiting prostaglandin synthesis is:

- acetylsalicylic acid

The LEAST important goal of pharmacologic therapy in the treatment of epilepsy is to:

- achieve seizure-free status

Following an acute overdose of acetaminophen (Tylenol), patients who are at significant risk for hepatotoxicity should receive:

- acteylcysteine

Beta-blockers, used for the prophylactic treatment of migraines, would NOT be contraindicated in a patient with a history of:

- acute coronary syndrome

For treatment of Bell's palsy, combination therapy is considered to be more beneficial and includes corticosteroids plus:

- acyclovir

Education for patients who are taking amantadine should NOT include:

- additional doses may be taken for symptom exacerbation

Oral levetiracetam (Keppra) is indicated for use as:

- adjunct treatment of partial onset seizures in adults and children

The medication class that does NOT lead to postural hypotension and possible syncope is:

- adrenergic agonists (Inotropes)

Clopidogrel (Plavix) is considered:

- an antiplatelet medication

To prevent further events, patients with transient ischemic attacks (TIAs) should be treated with:

- aspirin (Ecotrin)

A pediatric patient who is taking valproic acid (Depakene) may exhibit toxicity symptoms which would include:

- ataxia, irritability and somnolence

Syncope related to vasovagal symptoms is best treated with:

- beta blockers

Patients with mild chronic obstructive pulmonary disease may receive a beta-blocker for migraine prophylaxis as long as they are not currently taking a(n):

- beta-2-adrenergic agonist

In addition to the treatment of various forms of epilepsy, lamotrigine (Lamictal) is indicated in the treatment of:

- bipolar 1 disorder

The most common side effects related to benztropine (Cogentin) and trihexyphenidyl, used in the treatment of Parkinsonism, are:

- blurred vision and urinary retention

Patients receiving non-cardioselective beta blockers for migraine treatment are much more likely to experience:

- bronchial constriction

Acute tension-type headaches refractory to simple analgesics may respond to a combination of analgesics and:

- butalbital

Fioricet, indicated for the abortive treatment of tension-type headache, is a combination of acetaminophen:

- butalbital and caffeine

Oxcarbazepine (Trileptal) is structurally similar to:

- carbamazepine (Tegretol)

Non-selective beta-blockers used in migraine prophylaxis actively compete for beta receptors, inhibiting the binding of:

- catecholamine

Patients who are taking rasagiline (Azilect) for the treatment of Parkinson's disease should avoid other CYP1A2 inhibitors such as:

- ciprofloxacin (Cipro)

A patient who is taking valproic acid (Depakote) should have routine laboratory monitoring which includes a:

- complete blood count, Depakote level and liver function test

Phenobarbital, indicated for the treatment of epilepsy, is:

- contraindicated in patients with hypersensitivity to barbiturates

Sumatriptan (Imitrex), a serotonin (5-HT1) receptor agonist, is:

- contraindicated in patients with peripheral vascular disease

The pharmacological management that provides the greater clinical improvement of carpal tunnel syndrome is:

- corticosteroid (local injection)

Taking a triptan (5-HT1 agonist), such as sumatriptan (Imitrex), early in the headache cycle does NOT:

- decrease medication dependence and overuse syndrome

A patient started on lamotrigine (Lamictal) 4 weeks ago, and today presents with a mild rash on the upper left thigh. The nurse practitioner should:

- discontinue the lamotrigine immediately

The most common reason patients discontinue use of pregabalin (Lyrica) is:

- dizziness

A drug interaction may occur between carbamazepine (Tegretol) and:

- drospirenone/ethinyl estradiol (Yaz)

Common side effects related to pregabalin (Lyrica) include:

- edema and weight gain

Children who are receiving gabapentin (Neurontin) should be monitored for:

- emotional lability

Exercise caution before initiating pregabalin (Lyrica) in combination with:

- enalapril (Vasotec)

Due to increased cholinergic activity in patients treated with donepezil (Aricept), patients should be monitored for:

- gastrointestinal bleeding

Divalproex sodium (Depakote) for the prophylactic treatment of migraines:

- has been associated with polycystic ovarian syndrome (PCOS)

A patient presenting with a transient ischemic attack (TIA) is taking nifedipine (Adalat CC) for hypertension. Pharmacokinetics of nifedipine may be altered in patients with:

- hepatic impairment

Acetaminophen may be used to reduce fever in the presence of a febrile seizure. A severe complication of acetaminophen (Tylenol) is:

- hepatotoxicity

A patient who is taking carbamazepine (Tegretol) for trigeminal neuralgia presents with complaints of fatigue, muscle cramps and nausea. These are symptoms of:

- hyponatremia

Patients receiving oxcarbazepine (Trileptal) should be routinely monitored for:

- hyponatremia

Carbidopa and levodopa are the active ingredients in Sinemet used to treat Parkinson's disease. The addition of carbidopa:

- increases plasma half-life levodopa

Butalbital, one of the components of Fioricet, a mediation used to abort tension-type headaches:

- is a barbiturate that acts on the central nervous system

Ticlopidine (Ticlid), platelet aggregation inhibitor;

- is rarely used due to side effects limited efficacy compared to other agents

Patients receiving levetiracetam (Keppra) are NOT likely to experience the side effect of:

- jaundice

A patient receiving lamotrigine (Lamictal) for the treatment of epilepsy would NOT need routine monitoring of:

- lamotrigine levels

Ropinirole (Requip), used in the treatment of restless leg syndrome (RLS), is metabolized primarily in the:

- liver

Serotonin (5HT1) receptor agonists, or triptans:

- may cause hypertensive crisis even in patients without a history of hypertension.

Carbamazepine (Tegretol), used in the treatment of trigeminal neuralgia;

- may precipitate conduction disturbances on electrocardiograms (ECG).

Topiramate (Topamax), an antiepileptic drug:

- may reduce oral contraceptive effectiveness

Clindamycin (Cleocin) is NOT indicated in the treatment of:

- meningitis

Macrolide, such as clarithromycin (Biaxin), are NOT generally used to treat:

- meningitis

Ergotamine alkaloids, such as dihydroergotamine (Migranal), are indicated in the treatment of:

- migraine headaches (actue)

Pregabalin (Lyrica) is NOT approved for the treatment of:

- migraines with aura

Patients who experience greater than 7 to 9 tension-type headaches per month may be considered for maintenance therapy including:

- muscle relaxants and tricyclic antidepressants

Carbidopa/levodopa (Sinemet) for the treatment of Parkinson's disease is contraindicated in patients with:

- narrow-angle glaucoma

The most common short-term adverse effects of ropinirole (Requip) used in restless leg syndrome (RLS) include:

- nausea, vomiting, and fatigue

Patients taking topiramate (Topamax) are at high risk for developing:

- nephrolithiasis

The first-line treatment in acute tension-type headache is:

- non-steroidal anti-inflammatory drugs

During initiation of treatment and escalation of doses, pramipexole (Mirapex) and other dopamine agonists are know to cause:

- orthostatic hypotension

Chronic use of phenytoin (Dilantin) has been associated with:

- osteopenia

A patient who is receiving divalproex sodium (Depakote) reports acute abdominal pain accompanied by nausea and vomiting. This patient should be evaluated for:

- pancreatitis

Primidone (Mysoline) is metabolized into two active metabolites, one of which is:

- phenobarbital

The generic name for Lyrica is:

- pregabalin

Levetiracetam (Keppra), indicated in the adjunctive treatment of partial seizures, is:

- primarily excreted renal unchanged

Which medication does NOT have an indication for the treatment of Parkinson disease?

- primidone (Mysoline)

The primary beta-blocker indicated for the prophylactic treatment of migraine headaches is:

- propranolol hydrochloride (Inderal)

Patients who are taking carbidopa/levodopa (Siniment) for Parkinson's disease should be advised to avoid a diet high in:

- protein

Patients who are taking divalproex sodium (Depakote) and lamotrigine (Lamictal) are at higher risk developing:

- rash, including Stevens Johnson syndrome

The medication recommended for the rescue of refractory or cluster seizure activity is:

- rectal diazepam (Diastat)

Monitoring of patients receiving gabapentin (Neurontin) should include:

- renal function

Pramipexole (Mirapex), a dopamine agonist, is indicated in the treatment of:

- restless leg syndrome and Parkinson disease

Beta-blockers are contraindicated in patients with:

- second-degree heart block

Triptans, such as sumatriptan (Imitrex), should NOT be administered concomitantly with:

- selective serotonin reuptatke inhibitors (SSRIs)

Sumatriptan (Imitrex) is classified as a(n);

- serotonin (5-HT1) receptor agonist

Monitoring for side effects of topiramate (Topamax) includes:

- serum bicarbonate and chloride

Propranolol hydrochloride (Inderal) for the treatment of migraines:

- should be tapered if discounted

The mechanism of action of pramipexole (Mirapex) is to:

- stimulate dopamine receptors in the striatum

At each follow-up visit for patients who are taking carbidopa/levodop (Sinemet), the provider should specifically inquire about:

- sudden sleep onset and gambling or sexual urges

A patient who is taking beta-blockers for the prophylactic treatment of migraine headache does NOT need to be monitored for:

- tachypnea

Benztropine (Cogentin), an anticholinergic, is NOT recommended for use patients with:

- tardive dyskinesia

A common adverse reaction to clopidogrel (Plavix) is:

- thrombotic thrombocytopenia purpura

Ergotamine alkaloids for the treatment of migraines are safe to administer with:

- topiramate (Topamax)

Carbamazepine (Tegretol) is indicated in the treatment of:

- trigeminal neuralgia

The first-line pharmacological option for the treatment of generalized tonic-clonic seizures is:

- valproic acid (Depakote)

Which of the following is a non-dihydropyridine calcium channel-blocker?

- verapamil (Calan)

Carbidopa/levodopa (Sinemet) for the treatment of Parkinson's disease is a(n):

-dopaminergic agent

Patients who require oral corticosteroids for the treatment of Bell's Palsy should be instructed to take the medications:

-with food

Which of the following statements is NOT true about antiepileptic drugs (AEDs)?

Dosing of antiepiletics should be based on therapeutic drug levels.


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