Skin Cancer

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immunosuppressed, xeroderma pigmentosa

individuals who are _____________________ as a result of chemotherapy or organ transplantation or have ____________________ (genetic disease of DNA repair which makes ability to repair damage done by UV radiation less efficient) are at increased risk for squamous cell carcinoma

men

is melanoma more common in men or women?

basal cell carcinoma

least aggressive type of skin cancer

melanoma

least common type of skin cancer

3, 75

melanoma accounts for _____% of skin cancers, but causes more than _______% of skin cancer deaths

1:55

________ will be diagnosed with melanoma during their lifetime

90

________% of non-melanoma skin cancers are associated with exposure to UV radiation from the sun

1:5

_________ americans will develop skin cancer in the source of their lifetime

1:41, 1:61

_________ men and ________ women will develop melanoma in their life

merkel cell carcinoma

a rare skin cancer that usually appears as a flesh-colored or bluish-red nodule, often on the face, head or neck

8:10

about ________ skin cancers are basal cell carcinomas

UVA

aging ray

sebaceous carcinoma

an egressive, uncommon, cutaneous tumor arising from sebaceous glands in the skin

62,000, 8,000

approximately ______________ melanomas will be diagnosed this year with nearly ___________ resulting in death

head, neck

basal cell carcinomas usually develop on sun-exposed areas and especially on the _________ and __________

40-60

between __________% of americans who live at age 65 will have either basal cell carcinoma or squamous cell carcinoma at least once

are not

border of melanomas (ARE/ARE NOT) ___________ smooth, round and uniform as in normal nevi

UVB

burning ray

eccrine carcinoma

carcinoma of the eccrine sweat gland

merkel cell carcinoma

first sign of this skin cancer is usually a fast-growing, painless nodule on the skin; may be shiny, may appear in shades of red, blue, purple, or flesh-colored

1

in african americans, there are ____ melanoma cases for every 100,000 people

22

in caucasians, there are _____ melanoma cases for every 100,000 people

children, adults

in non-caucasians, there is a higher risk of melanoma in _____________ than ___________

asymptomatic, itching, 10mm, color, size, shape, pigmented lesion

melanoma is usually _____________ although ____________ may be an early manifestation. the majority of lesions are greater than __________ in diameter and the most important clinical signs of disease is change in _________, _________ or ___________ in a ___________________

touch

merkel cells thought to be associated with the sense of

1 million

more than ______________ skin cancers are diagnosed annually

melanoma

most aggressive type of skin cancer

skin cancer

most common form of cancer in the US

basal cell carcinoma

most commonly diagnosed skin cancer

eccrine carcinoma

rare; accounts for 1 of 13,000 specimens submitted to dermatopathology lab; only several hundred cases reported; commonly presents as wart lesion, plaques, or polypoid growths

2:10, 250,000, 2,500

squamous cell carcinoma accounts for _________ skin cancers, approximately _____________ cases per year, resulting in approximately ___________ deaths annually

1.3 million

squamous/basal cell incidence

1 billion

the total direct cost associated with treatment for non-melanoma skin cancers is more than ______________ dollars annually

11,200

total deaths from skin cancer

39, 40

until age ______, women are twice as likely to develop melanoma than men, but starting at age ______, melanoma incidence in men exceeds incidence in women

UV rays, pre-existing nevi, hereditary factors, carcinogens

4 causes/predispositions for melanoma

sebaceous carcinoma

75% arise in periocular reino; high tendency for local recurrence; often mistaken for benign entities; can be caused by radiation; can spread directly to sinuses and brain

asymmetry, border, color, diameter, elevation

ABCDE of skin cancer


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