Ch. 23

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CRH stimulates the release of

ACTH

What is the most important hormone causing an increase in serum Ca2+?

PTH

The pituitary hormone that triggers the release of thyroid hormone from the thyroid gland is

TSH.

How is the hypothalamic control of growth hormone (GH) release different from the control of TSH and ACTH?

The hypothalamus releases both stimulatory and inhibitory tropic hormones for GH, whereas it only releases stimulatory hormones for TSH and ACTH.

What is the effect of deiodinases on thyroid hormone function?

They convert T4 to the more active T3 in target cells.

C cells of the thyroid gland secrete ________.

calcitonin

Elevated levels of calcium ion in the blood stimulate the secretion of the hormone

calcitonin

A hormone that can lower blood levels of calcium ion is

calcitonin.

Vitamin D is a precursor in the synthesis pathway of ________.

calcitriol.

The adrenal medulla produces

catecholamines

The common precursor for all steroid hormones is ________.

cholesterol

The most important metabolic effect of ________ is protection against ________, crucial to surviving significant stress.

cortisol, hypoglycemia

mental retardation associated with infantile hypothyroidism

cretinism

Hyperthyroidism

decreases protein synthesis.

caused by growth hormone deficiency in childhood

dwarfism

Acromegaly is associated with ________.

excess growth hormone

Which of the following is a sign or symptom of hyperthyroidism?

exophthalmos

associated with Graves' disease

exophthalmus

All of the hormones secreted by the adrenal gland play a major role in growth and metabolism.

false

caused by growth hormone excess in childhood

giantism

Excess growth hormone prior to puberty would result in

giantism.

Without cortisol's permissive effect on ________, an animal would die.

glucagon

caused by elevation of TSH

goiter

Thyroid hormone contains the mineral

iodine.

Which is associated with hyperthyroidism?

irritability and weight loss

easily observable symptom of hypercortisolism

moon face

The C cells of the thyroid gland produce

only calcitonin.

Cholesterol is a precursor for the synthesis of

progesterone, aldosterone, and estradiol.

The action of a hormone on a target cell involves effects on

receptor and nonreceptor proteins.

Which of the following IS a physiological function of calcium?

-cofactor in the coagulation cascade -signal molecule -part of intercellular cement that holds cells together at tight junction -affects the excitability of neurons

The hypothalamic-pituitary-adrenal pathway begins with secretion of ________ into the hypothalamic-hypophyseal portal system and transported to the ________.

-cortiotropin-releasing hormone -anterior pituitary

Which of the following are factors that affect normal body growth?

-growth hormone -adequate diet -genetics -absence of stress

Parathyroid hormone

-increases the rate of calcium absorption. -raises the level of calcium ion in the blood. -decreases the rate of calcium excretion. -stimulates osteoclast activity.

________ is a result of deficient thyroid hormone secretion in infancy.

Cretinism

may result from adrenal tumor

Cushing's disease

hyperthyroidism

Graves' disease

caused by growth hormone excess in adulthood

acromegaly

Excess secretion of growth hormone during adulthood will cause

acromegaly.

This condition results from excess androgens in females.

adrenogenital syndrome

A rise in cortisol would cause each of the following except one. Identify the exception.

increased ACTH levels

The parathyroid glands produce a hormone that

increases the level of calcium ions in the blood.

Increased blood calcium levels result in increased

secretion of calcitonin.

Crossover effects are sometimes seen among

steroid hormones

Cortisol has the following effects:

suppresses the immune system and influences brain function.


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