Chapter 18 blood

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68) ________ is a condition in which the oxygen-carrying capacity of the blood is reduced. a) Leukemia b) Thrombocytopenia c) Anemia d) Leukopenia e) Polycythemia

Anemia

3) The hematocrit is ____________ of the total blood volume. a) less than 1% b) 47% to 63% c) 25% to 37% d) 42% to 45% e) 37% to 52%

E) 37% to 52%

117) Which of the following lab values would be a sign of anemia? a) 3.5 million RBC b) 7.0 million RBC c) 4,000 WBC d) 10,000 WBC e) all of the above

a) 3.5 million RBC

30) A woman's first pregnancy is normal but her second pregnancy results in hemolytic disease of the newborn (HDN), or erythroblastosis fetalis. The second child needed a transfusion to completely replace the agglutinating blood. The mother is most likely type _____ and both children are most likely _____. a) A, Rh-negative; B, Rh-positive b) A, Rh-positive; B, Rh-negative c) O, Rh-negative; AB, Rh-negative d) AB, Rh-positive; O, Rh-negative e) AB, Rh-positive; O, Rh-positive

a) A, Rh-negative; B, Rh-positive

83) A person with type A blood has a) B agglutinins in their plasma. b) B agglutinogens on their red blood cells. c) Agglutinins on their red blood cells. d) Agglutinogens in their plasma. e) The ability to receive AB blood cells.

a) B agglutinins in their plasma.

134) A molecule that activates plasminogen prior to the time that a clot forms would: a) Cause clot formation to take longer. b) Have no effect on the rate of clot formation. c) Cause clot formation to proceed faster.

a) Cause clot formation to take longer

4) _____________ is not found in plasma. a) Glycogen b) Fibrinogen c) Glucose d) Urea e) Albumin

a) Glycogen

80) The percentage of whole blood occupied by cellular elements is the a) Hematocrit. b) Specific gravity. c) Differential cell count. d) Packed volume. e) Viscosity.

a) Hematocrit.

138) Mary is tested for the amount of hemoglobin in her blood. The test results indicate that her hemoglobin level is 16 g/dL of blood. This value implies that: (a) a) Her hemoglobin level is normal. b) She may be suffering from a form of leukemia. c) She is suffering from anemia. d) She has fewer than normal red blood cells than normal. e) Her hematocrit is probably lower than normal.

a) Her hemoglobin is normal

55) A person has a low blood volume is said to be a) Hypovolemic. b) Isovolemic. c) Normovolemic. d) Hypervolemic. e) Antivolemic.

a) Hypovolemic.

93) Platelets are formed from cells in the bone marrow called: a) Megakaryocytes. b) Normoblasts. c) Lymphoblasts. d) Erythroblasts. e) Myeloblasts.

a) Megakaryocytes

87) ________ are large phagocytic white cells that spend most of their time outside the blood as fixed and free phagocytic cells. a) Monocytes b) Basophils c) Lymphocytes d) Neutrophils e) Eosinophils

a) Monocytes

102) The enzyme that can digest the fibrin strands and cause erosion of the clot's foundation is: a) Plasmin. b) Heparin. c) Urokinase. d) Streptokinase. e) Thrombin.

a) Plasmin

69) A condition in which the hematocrit is elevated and the blood volume is normal would be a) Polycythemia. b) Leukocytosis. c) Anemia. d) Leukemia. e) Thrombocytosis.

a) Polycythemia

62) Agranular leukocytes are formed in a) Red bone marrow. b) The thymus. c) The spleen. d) The liver. e) Yellow bone marrow.

a) Red bone marrow.

78) ________ are immature erythrocytes that are sometimes found in peripheral blood samples. a) Reticulocytes b) Erythroblasts c) Normoblasts d) Myeloblasts e) Band cells

a) Reticulocytes

97) Most of the procoagulants that are required for clotting are synthesized by: a) The liver. b) The kidneys. c) Megakaryocytes. d) Platelets. e) The spleen

a) The Liver

52) The combination of plasma and formed elements is called a) Whole blood. b) Packed blood. c) Extracellular fluid. d) Lymph. e) Serum.

a) Whole blood

113) Which transport globulin carries triglycerides in the blood? a) apolipoprotein b) metalloprotein c) hormone-binding protein d) steroid-binding protein e) none of the above

a) apolipoprotein

18) Anemia has these potential consequences except a) blood viscosity is increased. b) the individual is lethargic. c) blood osmolarity is reduced. d) blood resistance to flow is reduced. e) more fluid transfers from the bloodstream to the intercellular spaces.

a) blood viscosity is increased

7) Serum is essentially identical to plasma except for the absence of __________. a) fibrinogen b) nitrogenous wastes c) platelets d) glucose e) albumin

a) fibrinogen

26) rhoGAM is an antibody given to Rh- women who give birth to Rh+ children. RhoGAM is what type of plasma protein? a) gamma (.) globulin b) beta (ß) globulin c) alpha (a) globulin d) fibrinogen e) albumin

a) gamma (.) globulin

23) The ABO blood group is determined by ______ in the plasma membrane of RBCs. a) glycolipids b) glycoproteins c) antibodies d) antigen-antibody complexes e) agglutinins

a) glycolipids

14) An increased erythropoietin (EPO) output by the kidneys would lead to all of the following except a) increased hypoxemia. b) increased blood osmolarity. c) increased RBC production. d) increased blood viscosity. e) increased hematocrit.

a) increased hypoxemia.

108) Areas where smooth muscle cells store large quantities of lipid are called: a) plaque. b) thrombi. c) clots. d) occlusions. e) emboli.

a) plaque

35) Leukopoiesis begins with the differentiation of a) pluripotent stem cells (PPSCs). b) precursor cells. c) colony-forming units (CFUs). d) myeloblasts. e) lymphoblasts.

a) pluripotent stem cells (PPSCs)

43) All of these prevent the spontaneous formation of a clot except a) the presence of tissue thromboplastin. b) the smooth prostacyclin-coated endothelium of blood vessels. c) the dilution of thrombin when blood flows at a normal rate. d) the presence of antithrombin in plasma. e) the presence of heparin in plasma.

a) the presence of tissue thromboplastin

46) Most strokes and heart attacks are caused by the abnormal clotting of blood in an unbroken vessel. Moreover, a piece of the ____________ (clot) may break loose and begin to travel in the bloodstream as a(n) ______________. a) thrombus; embolus b) embolism; thrombus c) plaque; thrombus d) thrombosis; plaque e) plaque; embolus

a) thrombus; embolus

149) Blood aids in the regulation of body temperature. a) True b) False

a) true

81) The average amount of hemoglobin in the blood of an adult female is a) 5-10 g/dL of blood. b) 15-16 g/dL of blood. c) 20-25 g/dL of blood. d) 30-40 g/dL of blood. e) More than 50 g/dL of blood.

b) 15-16 g/dL of blood.

6) _____________ would not decrease colloid osmotic pressure (COP) in blood. a) Severe liver failure b) A diet predominantly based on red meat c) Starvation d) An extremely low-protein diet e) Hypoproteinemia

b) A diet predominantly based on red meat

24) Type A blood can safely donate RBCs to _____nd can receive RBCs of type ______. a) O; AB b) AB; O c) A; B d) B; A e) O; O

b) AB:0

125) Hemolytic disease of the newborn may result if: a) Both the father and the mother are Rh positive. b) An Rh negative mother carries an Rh positive fetus. c) Both the father and the mother are Rh negative. d) The mother is Rh positive and the father is Rh negative. e) An Rh negative mother carries Rh negative twins.

b) An Rh- mother carries an Rh+ fetus

28) An individual has type B, Rh-positive blood. The individual has _____ antigen(s) and can produce anti-_____ antibody(ies). a) A and D; B b) B and D; A c) B; A and D d) A; B and D e) D; A and B

b) B and D; A

34) _____ aid in the body's defense processes by secreting histamine (vasodilator) and heparin (anticoagulant). a) Eosinophils b) Basophils c) Neutrophils d) Platelets e) Monocytes

b) Basophils

66) More than 95 percent of the protein in a red blood cell is a) Porphyrin. b) Hemoglobin. c) Albumin. d) Immunoglobulin. e) Fibrinogen.

b) Hemoglobin

50) Blood is composed of all of the following, except a) Cell fragments. b) Interstitial fluid. c) Blood cells. d) Plasma. e) Formed elements.

b) Interstitial fluid

88) The white blood cells that are important in producing antibodies are the: a) Basophils. b) Lymphocytes. c) Neutrophils. d) Eosinophils. e) Monocytes

b) Lymphocytes

91) A hormone that stimulates the activity of the monocyte macrophage line is: a) Multi-CSF. b) M-CSF. c) Thymosin. d) GM-CSF. e) G-CSF

b) M-CSF

79) Erythropoiesis increases when a) Carbon dioxide levels in the blood decrease. b) Oxygen levels in the blood decrease. c) Oxygen levels in the blood increase. d) Protein levels in the blood increase.

b) Oxygen levels in the blood decrease.

82) A person's blood type is determined by the a) Number of specific molecules on the cell membrane. b) Presence or absence of specific molecules on the cell membrane. c) Shape of the red blood cells. d) Chemical character of the hemoglobin. e) Size of the red blood cells.

b) Presence or absence of specific molecules on the cell membrane.

The most abundant proteins in blood plasma are a) lipoproteins. b) albumins. c) globulins. d) transport proteins. e) fibrinogens.

b) albumins.

128) In which of the following situations would you expect the blood level of bilirubin to be above normal? a) a person suffering from anemia b) an alcoholic with a damaged liver

b) an alcoholic with a damaged liver

121) After losing a fair amount of blood as a result of an accident, one would expect: a) Increased levels of tissue plasminogen activator. b) An increased reticulocyte count. c) An increased erythrocyte count. d) A decreased reticulocyte count. e) A decreased erythrocyte count.

b) an increased reticulocyte count

31) These are the least abundant formed elements. a) platelets b) basophils c) erythrocytes d) neutrophils e) eosinophils

b) basophils

19) What is the final product of the breakdown of the organic nonprotein moiety of hemoglobin? a) biliverdin b) bilirubin c) globin d) heme e) iron

b) bilirubin

150) The RBCs of a fetus and an adult are the same. a) True b) False

b) false

115) Your patient is on coumadin therapy (an anticoagulant) for a blood clot in the leg. Which type of plasma protein would you suspect is low? a) serum b) fibrinogen c) plasma protein d) globulin e) albumin

b) fibrinogen

58) Plasma proteins that are necessary for blood clotting are the a) albumins. b) fibrinogens. c) lipoproteins. d) Metalloproteins. e) Immunoglobulins.

b) fibrinogens.

127) Excess iron is stored in the liver and bone marrow in: a) Albumin. b) Hemosiderin. c) Transferrin. d) Hemoglobin. e) Bilirubin.

b) hemosiderin

130) A decrease in the amount of transferrin in the blood would result in: a) Increased storage of iron in the liver. b) Increased absorption of iron from the intestine. c) Increased amounts of hemosiderin in the liver. d) Increased levels of bilirubin in the blood. e) Increased amounts of hemoglobin in the blood.

b) increased absorption of iron from the intestine

41) Thromboplastin a) initiates the intrinsic pathway of coagulation. b) initiates the extrinsic pathway of coagulation. c) converts prothrombin into thrombin. d) acts as a potent vasoconstrictor to reduce blood loss. e) dissolves the clot after the tissue has healed.

b) initiates the extrinsic pathway of coagulation.

16) All these can lead to polycythemia except a) cancer of the erythropoietic line of the red bone marrow. b) iron deficiency. c) dehydration. d) emphysema. e) excessive aerobic exercise.

b) iron deficiency.

142) Which of the following would you expect to see in elevated numbers in a peripheral blood sample after donating a pint of blood to the Red Cross? a) erythrocytes b) reticulocytes c) neutrophils d) platelets e) lymphocytes

b) reticulocytes

141) What effect would a drug that interferes with protein synthesis have on the development of red blood cells? a) The cells would be round like spheres. b) The cells formed would not be able to carry as much oxygen as normal. c) The cells formed would have abnormal cell membranes. d) The cells formed would carry larger amounts of carbon dioxide. e) Fewer cells than normal would be formed.

b) the cells formed would not be able to carry as much oxygen as normal

144) People who suffer from hemophilia A fail to produce a functional factor VIII; as a result: a) Their clotting times are shorter than normal. b) They do not have a functional intrinsic pathway. c) They do not have a functional extrinsic pathway. d) They do not have a functional common pathway. e) Their blood will clot at a rate faster than normal.

b) they do not have a functional intrinsic pathway

39) Platelets do not secrete a) procoagulants (clotting factors). b) thrombopoietin. c) growth factors. d) vasoconstrictors. e) chemicals that attract neutrophils.

b) thrombopoietin.

___________ is a protein not commonly found in plasma. a) Albumin b) Hemoglobin c) Transferrin d) Prothrombin e) Fibrinogen

b)Hemoglobin

37) A total count above ____________ WBCs/µL is called leukocytosis. a) 100,000 b) 50,000 c) 10,000 d) 5,000 e) 1,000

c) 10,000

64) The average lifespan of a red blood cell is a) 1 week. b) 1 month. c) 4 months. d) 6 months. e) 1 year

c) 4 months.

109) The cardiovascular system of an adult female contains how much blood? a) 2-3 L b) 3-4 L c) 4-5 L d) 5-6 L e) 6-7 L

c) 4-5L

54) The total volume of blood in the body of a 70-kg man is approximately ________ liters. a) 25-30 b) 10-15 c) 5-6 d) 2-4 e) less than 2

c) 5-6

100) The common pathway of coagulation begins with the: a) Sticking of platelets to damaged tissue. b) Activation of a proenzyme exposed to collagen. c) Activating of a clotting factor that converts prothrombin to thrombin. d) Activation of a clotting factor that converts fibrinogen to fibrin. e) Release of tissue factor by damaged endothelium

c) Activating of a clotting factor that converts prothrombin to thrombin

56) The chief difference between plasma and interstitial fluid involves the a) Quantity of electrolytes. b) Concentration of glucose. c) Concentration of oxygen and proteins. d) Quantity of organic wastes. e) Amount of water.

c) Concentration of oxygen and proteins.

90) A hormone that stimulates the production of granulocytes is: a) M-CSF. b) GM-CSF. c) G-CSF. d) Multi-CSF. e) Thymosin.

c) G-CSF

126) The porphyrin ring of heme contains an atom of: a) Copper. b) Magnesium. c) Iron. d) Sodium. e) Calcium.

c) Iron

131) During a viral infection you would expect to see increased numbers of: a) Neutrophils. b) Basophils. c) Lymphocytes. d) Eosinophils. e) Thrombocytes.

c) Lymphocytes

129) In some newborn infants it is not uncommon for the spleen to destroy red blood cells faster than the liver can conjugate the bilirubin. This situation would result in: a) More bilirubin appearing in tissue fluid. b) More bilirubin appearing in the bile. c) More bilirubin appearing in the blood plasma. d) More bilirubin appearing in the feces. e) More bilirubin appearing in the urine.

c) More bilirubin appearing in the blood plasma

85) The most numerous white blood cells in peripheral circulation are the a) Monocytes. b) Eosinophils. c) Neutrophils. d) Lymphocytes. e) Basophils.

c) Neutrophils.

27) The universal donor of RBCs, but not necessarily plasma, is a) AB, Rh-negative. b) AB, Rh-positive. c) O, Rh-negative. d) O, Rh-positive. e) ABO, Rh-negative.

c) O, Rh-Negative

123) A hematocrit provides information on: a) Plasma composition. b) Clotting factors. c) Packed cell volume. d) Blood type. e) The types of leukocytes

c) Packed Cell Volume

73) Most of the iron that is removed from degraded hemoglobin is a) Stored in yellow bone marrow. b) Excreted by the intestines. c) Recycled to the bone marrow. d) Excreted by the kidneys. e) Excreted by the liver.

c) Recycled to the bone marrow

124) In adults, the only site of red blood cell production, and the primary site of white blood cell formation, is the: a) Spleen. b) Liver. c) Red bone marrow. d) Yellow bone marrow. e) Thymus.

c) Red Bone Marrow

59) Red blood cells are formed in a) The liver. b) Yellow bone marrow. c) Red bone marrow. d) The spleen. e) Lymph nodes.

c) Red bone marrow.

Which of the following statements concerning red blood cells is false? a) Red cells are biconcave discs. b) Red cells can form stacks called rouleaux. c) Red cells have a large nucleus. d) Red cells lack mitochondria. e) Red cells are specialized for carrying oxygen

c) Red cells have a large nucleus

17) __________ is more likely to cause anemia than any of the other factors below. a) High altitude b) Air pollution other than by carbon monoxide c) Renal disease d) Smoking e) Any factor that creates a state of hypoxemia

c) Renal disease

106) A person whose platelet count is 100,000/mm3 blood would be suffering from: a) Thrombocytosis. b) Leukocytosis. c) Thrombocytopenia. d) Leukopenia. e) Hemocytosis.

c) Thrombocytopenia

45) The structural framework of the blood clot is formed by a) soluble fibrinogen. b) soluble fibrin. c) a fibrin polymer. d) a fibrinogen polymer. e) a thrombin polymer.

c) a fibrin polymer.

71) An anemia that is caused by failure of the bone marrow to produce new red blood cells is called ________ anemia. a) hemorrhagic b) pernicious c) aplastic d) sickle cell e) dietary

c) aplastic

67) The function of hemoglobin is to a) Protect the body against infectious agents. b) Aid in the process of blood clotting. c) Carry oxygen. d) Carry nutrients from the intestine to the body's cells. e) both A and C

c) carry oxygen

2) The buffy coat does not contain a) lymphocytes. b) granulocytes. c) erythrocytes. d) agranulocytes. e) platelets.

c) erythrocytes.

95) The main event of the platelet phase is: a) Activation of fibrinogen. b) Clot retraction. c) Formation of a platelet plug. d) Vascular spasm. e) Contraction of platelets.

c) formation of a platelet plug

40) The cessation of bleeding is specifically called a) vascular spasm. b) homeostasis. c) hemostasis. d) platelet plug formation. e) blood clotting (coagulation).

c) hemostasis.

139) A constriction of the arteries that carry blood to the kidneys would result in: a) Decreased erythropoiesis. b) Increased numbers of lymphocytes. c) Increased erythropoiesis. d) Anemia. e) Decreased elimination of vitamin K.

c) increased erythropoisesis

112) Transferrin is an example of which transport globulin? a) steroid-binding protein b) hormone-binding protein c) metalloprotein d) apolipoprotein e) none of the above

c) metalloprotein

9) Myeloid hemopoiesis in adults happens in the a) thymus. b) spleen. c) red bone marrow. d) yellow bone marrow. e) liver.

c) red bone marrow.

15) Many RBCs die in the a) stomach and small intestine. b) red bone marrow. c) spleen and liver. d) lymph nodes and thymus. e) stomach and liver.

c) spleen and liver.

114) Which transport globulin transports testosterone in a male? a) apolipoprotein b) hormone-binding protein c) steroid-binding protein d) metalloprotein e) none of the above

c) steroid-binding protein

21) A deficiency of _____________ can cause pernicious anemia. a) vitamin C b) iron c) vitamin B12 d) EPO secretion e) folic acid

c) vitamin B12

A normal adult hematocrit would be a) 100. b) 75. c) 66. d) 45. e) 10.

d) 45.

110) Water composes ______ percent of the plasma volume. a) 43 b) 87 c) 50 d) 92 e) 65

d) 92

5) _____________ is the most abundant protein in plasma. a) Insulin b) Creatine c) Bilirubin d) Albumin e) Creatinine

d) Albumin

86) White blood cells that release histamine at the site of an injury are a) Monocytes. b) Eosinophils. c) Lymphocytes. d) Basophils. e) Neutrophils.

d) Basophils.

96) ______ involves a complex sequence of steps leading to the conversion of fibrinogen to fibrin. a) Retraction b) Fibrinolysis c) The platelet phase d) Coagulation e) Vascular spasm

d) Coagulation

76) The process of red blood cell production is called a) Hemocytosis. b) Erythrocytosis. c) Erythropenia. d) Erythropoiesis. e) Hematopenia.

d) Erythropoiesis.

63) Red blood cell production is regulated by the hormone a) Angiotensin I. b) Thymosin. c) Cobalamin. d) Erythropoietin. e) M-CSF.

d) Erythropoietin.

49) Functions of the blood include all of the following, except a) Restricting fluid loss. b) Body defense. c) Regulation of pH and electrolyte concentration of interstitial fluids. d) Generation of body heat. e) Transport of nutrients and wastes.

d) Generation of body heat.

133) Rat poison contains a toxin that blocks the liver's ability to utilize vitamin K. Animals that consume rat poison would die of: a Aplastic anemia. b) Thrombocytopenia. c) Asphyxiation. d) Hemorrhage. e) Acidosis

d) Hemorrhage

84) All of the following are true of neutrophils, except that they are a) Phagocytic. b) Active in fighting bacterial infections. c) Also known as polymorphonuclear leukocytes. d) Important in coagulation. e) Granular leukocytes.

d) Important in coagulation.

74) In adults, erythropoiesis primarily takes place in a) The liver. b) Yellow bone marrow. c) The spleen. d) Myeloid tissue. e) The kidneys.

d) Myeloid tissue.

60) Stem cells responsible for the production of most white blood cells originate in the a) Thymus. b) Lymph tissue. c) Liver. d) Red bone marrow. e) Spleen.

d) Red bone marrow.

98) The extrinsic pathway of coagulation is activated by the: a) Conversion of prothrombin to thrombin. b) Release of heparin from the liver. c) Activation of a proenzyme exposed to collagen. d) Release of tissue factor by damaged endothelium. e) Sticking of platelets to damaged tissue.

d) Release of tissue factor by damaged epithelium

72) Aged and damaged erythrocytes are broken down by the a) Thymus gland. b) Digestive tract. c) Kidneys. d) Spleen. e) both A and C

d) Spleen.

61) Stem cells responsible for the process of lymphopoiesis are located in all of the following, except a) The thymus. b) The red bone marrow. c) The spleen. d) The kidney. e) The lymph nodes.

d) The kidney.

47) __________ participates in the extrinsic mechanism only. a) Calcium b) Prothrombin activator c) Prothrombin d) Thromboplastin e) Thrombin

d) Thromboplastin

22) Sickle-cell disease is not a) caused by a recessive allele that modifies the structure of hemoglobin. b) a hereditary hemoglobin defect. c) advantageous to protect carriers against malaria. d) a cause of malaria. e) a cause of anemia.

d) a cause of malaria.

20) Correction of hypoxemia is regulated by a) a self-amplifying mechanism. b) an enzymatic amplification. c) a positive feedback loop. d) a negative feedback loop. e) a cascade effect.

d) a negative feedback loop.

116) Which of the following proteins are found in plasma? a) Prolactin (*hydrophobic) b) Glycoprotein (*hydrophilic) c) luteinizing hormone (*hydrophilic) d) all of the above e) none of the above

d) all of the above

120) A drop of deoxyhemoglobin blood is what color? a) light blue b) dusky orange c) red d) burgundy e) blue

d) burgundy

65) The function of red blood cells is to a) Remove nitrogenous wastes from active tissues. b) Remove nitrogen from active cells. c) Carry nutrients from the digestive system to the body's cells. d) Carry oxygen from the lungs to the body's cells. e) Defend the body against infectious organisms.

d) carry oxygen from the lungs to the body's cells

36) Some lymphocytes can survive for a) days. B. weeks. b) months. c) years. d) decades.

d) decades.

38) All these can cause leukopenia except a) acquired immunodeficiency syndrome (AIDS). b) lead poisoning. c) radiation therapy. d) dehydration. e) immunosuppressant drugs.

d) dehydration.

101) The process of fibrinolysis: a) Forms thrombi. b) Forms emboli. c) Activates fibrinogen. d) Dissolves clots. e) Draws torn edges of damaged tissue closer together.

d) dissolves clots

92) Platelets function in all of the following, except: a) Contraction after clot formation. b) Forming temporary patches in injured areas. c) Initiating the clotting process. d) Dissolving a formed clot. e) Transporting chemicals important for clotting.

d) dissolving a formed clot

89) White blood cells that increase in number during an allergic reaction or in response to parasitic infections are the: a) Monocytes. b) lymphocytes. c) neutrophils. d) eosinophils. e) basophils.

d) eosinophils

10) The viscosity of blood is due more to _____________ than to any other factor. a) fibrin b) albumin c) sodium d) erythrocytes e) nitrogenous wastes

d) erythrocytes

103) Tissue thromboplastin is formed in the ________ pathway. a) intrinsic b) retraction c) common d) extrinsic e) fibrinolytic

d) extrinsic

77) Erythrocytes are formed from stem cells called a) Myeloid cells. b) Pronormoblasts. c) Band cells. d) Hemocytoblasts. e) Reticulocytes.

d) hemocytoblasts

111) Thyroid-binding protein is an example of which transport globulin? a) steroid-binding protein b) apolipoprotein c) metalloprotein d) hormone-binding protein e) none of the above

d) hormone-binding protein

132) A sample of tissue from an injury shows a large number of basophils. This would indicate that the tissue was: a) Infected by viruses. b) Being rejected. c) Abscessed. d) Inflamed. e) none of the above

d) inflamed

143) A physician examines a patient who is suffering from anemia. The hematocrit and hemoglobin concentrations are both low. The reticulocyte count is normal but the mean corpuscular volume and mean corpuscular hemoglobin concentration are both low. These results would indicate: a) Aplastic anemia. b) Pernicious anemia. c) Hemorrhagic anemia. d) Iron deficiency anemia. e) Macrocytic anemia.

d) iron deficiency anemia

13) If all the molecules of hemoglobin contained in RBCs were free in the plasma, a) it would considerably increase blood oxygen carrying capacity. b) it would facilitate delivery of oxygen into tissues supplied by small capillaries. c) it would facilitate oxygen diffusion into cells distant from blood capillaries. d) it would significantly increase blood osmolarity. e) it would drastically increase osmotic colloid pressure.

d) it would significantly increase blood osmolarity

32) These are the most abundant agranulocytes. a) macrophages b) eosinophils c) monocytes d) lymphocytes e) neutrophils

d) lymphocytes

148)Megan thinks she has an abscessed tooth. If she does, what type of white blood cell would you expect to see in elevated numbers in a differential count? a) lymphocytes b) eosinophils c) monocytes d) neutrophils e) Basophil

d) neutrophils

42) When a clot is no longer needed, fibrin is dissolved by a) prothrombin. b) thromboplastin. c) kallikrein. d) plasmin. e) platelet-derived growth factor (PDGF).

d) plasmin.

1) Blood does not a) transport a variety of nutrients. b) help to stabilize the pH of extracellular fluids. c) participate in the initiation of blood clotting. d) produce plasma hormones. e) help to regulate body temperature.

d) produce plasma hormones

119) Blood containing RBCs filled with oxyhemoglobin are which color? a) light blue b) blue c) dusky orange d) red e) burgundy

d) red

105) Which of the following vitamins is needed for the formation of clotting factors? a) vitamin E b) vitamin D c) vitamin B d) vitamin K e) vitamin A

d) vitamin K

118) Each hemoglobin molecule has _____ alpha chain(s) and _____ beta chain(s) of polypeptides. a) 3; 3 b) 3; 1 c) 1; 2 d) 2; 1 e) 2; 2

e) 2; 2

25) Type AB blood has ____________ RBC antigen(s). a) no b) anti-A and anti-B c) anti-A d) anti-B e) A and B

e) A and B

75) In adults, red bone marrow is located in the a) Sternum and ribs. b) Diaphysis of long bones. c) Body of vertebrae. d) all of the above e) A and C only

e) A and C only

99) The intrinsic pathway of coagulation is activated by the: (e) a) Release of tissue factor by damaged endothelium. b) Conversion of prothrombin to thrombin. c) Release of heparin from the liver. d) Sticking of platelets to damaged tissue. e) Activation of proenzyme exposed to collagen.

e) Activation of proenzyme exposed to collagen

51) The formed elements of the blood include a) Defense proteins. b) Clotting proteins. c) Albumins. d) Lipoproteins. e) Blood cells.

e) Blood cells.

135) How would a decrease in the concentration of calcium ions in the blood affect the process of hemostasis? a) Platelet plugs would fail to form. b) Coagulation would proceed more rapidly. c) Retraction would occur prematurely. d) Plasmin would fail to function. e) Coagulation would proceed more slowly.

e) Coagulation would proceed more slowly

107) A drifting blood clot is called a(n) a) Procoagulant. b) Thrombus. c) Plaque. d) Platelet plug. e) Embolus.

e) Embolus

57) Plasma proteins that are important in body defense are the a) albumins. b) fibrinogens. c) lipoproteins. d) Metalloproteins. e) Immunoglobulins.

e) Immunoglobulins.

Which organ releases the majority of the plasma proteins? a) pancreas b) gallbladder c) heart d) kidney e) liver

e) Liver

70) A red blood cell that contains normal amounts of hemoglobin would be called a) Hyperchromic. b) Normocytic. c) Macrocytic. d) Hypochromic. e) Normochromic.

e) Normochromic

137) Any disease that damages the stomach lining and interferes with gastric secretions could cause: a) Jaundice. b) Thrombocytopenia. c) Hemophilia. d) Leukocytosis. e) Pernicious anemia.

e) Pernicious anemia

The waste product bilirubin is produced from a) Globin chains of hemoglobin. b) Portions of heme molecules that contain iron. c) Abnormal proteins found in red blood cells. d) Iron found in hemoglobin molecules. e) Portions of heme molecules that do not contain iron.

e) Portions of heme molecules that do not contain iron.

145) A digestive disorder that impairs a person's ability to digest and absorb fats would interfere with a) The extrinsic pathway of clotting. b) Fibrinolysis. c) The process of retraction. d) The intrinsic pathway of clotting. e) The common pathway of clotting.

e) The common pathway of clotting.

136) When a person who lives in a city at sea level vacations in the Rocky Mountains, you would expect to observe an increase in: a) The density of their bone marrow. b) The number of platelets in their blood. c) The number of lymphocytes in their blood. d) Their white blood cell count. e) Their red blood cell count.

e) Their red blood cell count

53) Each of the following is a characteristic of whole blood, except a a) Temperature approximately 38 degrees Celsius. b) Dull red color if taken from a vein. c) Bright red color if taken from an artery. d) PH of 7.4. e) Viscosity about the same as water.

e) Viscosity about the same as water.

122) Eileen is a strict vegetarian who is experiencing erythropenia, a deficiency in the number of red blood cells. This condition is most likely the result of which of the following? a) too little vitamin K in the diet b) too much vitamin K in the diet c) lack of intrinsic factor d) too much iron in the diet e) a vitamin B12 deficiency

e) a vitamin B12 deficiency ---- due to lack of red meat consumption

Which of the following can be found in plasma? a) Lipids b) Enzymes c) fibrinogen d) electrolytes e) all of the above

e) all of the above

29) The main reason why an individual AB, Rh-negative cannot donate blood to an individual A, Rh-positive is because a) anti-A antibodies in the donor will agglutinate RBCs of the recipient. b) anti-A antibodies in the recipient will agglutinate RBCs of the donor. c) anti-B antibodies in the donor will agglutinate RBCs of the recipient. d) anti-D antibodies in the donor will agglutinate RBC of the recipient. e) anti-B antibodies in the recipient will agglutinate RBCs of the donor.

e) anti-B antibodies in the recipient will agglutinate the RBCs of the donor

146) Tom suffers from a severe liver disease. Which of the following symptoms would you expect to see as a result of this condition? a) accumulation of fluid in the tissue spaces of the extremities b) decreased levels of bilirubin in the blood c) decreased clotting ability d) all of the above e) A and C.

e) both A and C

140) The level of erythropoietin in the blood would rise due to all of the following, except: a) At high altitudes. b) During anemia. c) As a consequence of hemorrhage. d) When blood flow to the kidneys is disrupted. e) During periods of fasting.

e) during periods of fasting

94) Platelets are: a) Large cells with a prominent, indented nucleus. b) Small cells that lack a nucleus. c) Large cells that lack a nucleus. d) Small cells with a many-shaped nucleus. e) Fragments of large megakaryocyte cells.

e) fragments of large megakaryocyte cells

12) Most oxygen is transported bound to a) the plasma membrane of erythrocytes. b) alpha chains in hemoglobin. c) beta chains in hemoglobin. d) delta chains in hemoglobin. e) heme groups in hemoglobin.

e) heme groups in hemoglobin.

104) Platelet thromboplastin is formed in the ________ pathway. a) fibrinolytic b) extrinsic c) common d) retraction e) intrinsic

e) intrinsic

48) Most clotting factors are synthesized in the a) spleen. b) red bone marrow. c) perivascular tissue. d) kidneys. e) liver.

e) liver.

33) The differential count of ____typically increases in response to bacterial infections. a) basophils b) monocytes c) erythrocytes d) eosinophils e) neutrophils

e) neutrophils

44) Platelets release ____________, a chemical vasoconstrictor that contributes to the vascular spasm. a) heparin b) thrombin c) thromboplastin d) prostacyclin e) serotonin

e) serotonin

8) Tissues can become edematous (swollen) when a) colloid osmotic pressure (COP) is high. b) there is hyperproteinemia. c) the concentration of sodium and proteins in blood is high. d) hematocrit is high. e) there is a dietary protein deficiency.

e) there is a dietary protein deficiency.

11) Erythrocytes transport oxygen and a) defend the body against pathogens. b) initiate blood clotting. c) regulate erythropoiesis. d) transport nutrients. e) transport some carbon dioxide.

e) transport some carbon dioxide.


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