🎃🎃🖤💚MHC 11💚🖤🎃🎃
Antigen recognition
Inactive T cell binding to a specific MHC- antigen complex
Antigen recognition
Inactive T cells have receptors that recognize either class I or class II MHC proteins when they are bound to specific antigens
Class II MHC proteins
antigen-presenting cells (APCS) Examples: monocyte-macrophages dendritic cells
Antigen presentation with class II МНС 2.Phagocytic APCS engulf the extracellular pathogens.
1. Lysosomal action produces antigenic fragments.
Classes of MHC proteins 1. Class I MHC proteins Present in membranes of all nucleated cells Triggered by viral or bacterial infection of a body cell
2. Class II MHC proteins Present only in membranes of 🐠antigen-presenting cells (APCS)🐠 Ex:monocyte-macrophages,dendritic cells Appear only when the cell is processing antigens
Antigen presentation with class II МНС 1. Phagocytic APCS engulf 🐠the extracellular pathogens.
2. Lysosomal action produces 🐠antigenic fragments.
Antigen presentation with class II МНС 1.Phagocytic APCS engulf the extracellular pathogens. 2. Lysosomal action produces antigenic fragments.
3. The endoplasmic reticulum produces class II MHC proteins.
Antigen presentation with class II МНС 3. The endoplasmic reticulum produces 🐠class II MHC proteins.
4. Antigenic fragments are bound 🐠to class II MHC proteins.
Antigen presentation with class II МНС 4. Antigenic fragments are bound to class II MHC proteins.
5. Antigenic fragments are displayed by class I MHC proteins on the plasma membrane.
Antigen presentation with class II МНС 4. Antigenic fragments are bound 🐠 to class II MHC proteins.
Antigen presentation with class II МНС 5. Antigenic fragments are displayed by 🐠class I MHC protein🚩plasma membrane.
Antigen recognition Inactive T cell binding to a specific MHC- antigen complex Inactive T cells have receptors that recognize either class I or class II MHC proteins when they are bound to specific antigens
Antigen recognition T cell will bind only to a complex containing the antigen that T cell is programmed to detect
Class II MHC proteins
Present only in membranes of antigen-presenting cells (APCS)
Antigen recognition
T cell will bind only to a complex containing the antigen that T cell is programmed to detect
Inactive T cell Infected body cell (including APCS)
💚T cell receptor 💚Antigen 💚MHC protein Antigen recognition- protein
