General and Oral Pathology: Quiz/Test Questions
B) The first statement is false. The second statement is false
30% of Sjogren Syndrome patients have a positive response to the rheumatoid factor. The rheumatoid factor is an antibody to IgA present in serum: A) The first statement is true. The second statement is false, B) The first statement is false. The second statement is false, C) Both statements are true, D) The first statement is false. The second statement is true.
The first statement is false. The second statement is true
30% of Sjogren syndrome patients have a positive response to the rheumatoid factor. The rheumatoid factor is an antibody to IgG present in serum.
B) Malignant tumor
A BLANK both invades and destroys surrounding tissue and has the ability to spread throughout the body: A) Benign tumor, B) Malignant tumor, C) Hypertrophy, D) Hyperplasia
B) Rarely
A basal cell carcinoma will BLANK metastasize: A) Never, B) Rarely, C) Often, D) Always
C) Chondroma
A benign tumor of cartilage is termed: A) Osteoma, B) Lipoma, C) Chondroma, D) Carcinoma
C) Adenoma
A benign tumor of salivary gland organ is termed: A) Leiomyoma, B) Lipoma, C) Adenoma, D) Papilloma
Bulla
A circumscribed, elevated lesion that is more than 5 mm in diameter, usually containing serous fluid
Fissure
A cleft or groove showing prominent depth
Leukoplakia
A clinical term for a white, plaque like lesion on the oral mucosa that cannot be rubbed off or diagnosed as a specific disease
Erythroplakia
A clinical term used to describe an oral lesion that appears as a smooth red patch or granular red and velvety patch and demonstrates epithelial dysplasia in 90% of cases
Macule
A flat lesion, not protruding above the surface of normal tissue, which is distinguished by a color different from that of the surrounding tissue
B) Appears clinically as a yellowish mass surfaced by a thin layer of epithelium
A lipoma: A) Is a tumor of peripheral nerve tissue, B) Appears clinically as a yellowish mass surfaced by a thin layer of epithelium, C) is found most commonly intramurally on the tongue, D) Occurs most often in men over 60
C) benign; squamous
A papilloma is a BLANK tumor derived from BLANK epithelium: A) benign; salivary gland, B) malignant; squamous, C) benign; squamous, D) malignant; odontogenic
Margination
A process during inflammation in which white blood cells move to the blood vessel wall is termed:
Multilocular
A radiographic term used to describe a lesion which extends beyond the confines of one distinct area and is defined as many lobes or parts somewhat fused together
Papule
A small, circumscribed lesion usually less than 1 cm in diameter that is elevated or protrudes above the surface of normal
Erythema multiforme
A target lesion on the skin is associated with which of the following diseases?
Both statements are false
Cytokines function to initiate phagocytosis. Cytokines serve to amplify the immune response and store memory of the encountered antigen
C) Tertiary
In cases of healing, if an infected injury is left open and the edges are not surgically joined until the infection is controlled; this process is referred to as healing by: A) Primary, B) Secondary, C) Tertiary
C) Lupus erythematosus
In the mildest form of this autoimmune disease, oral lesions appear as erythematous plaques or erosions. White striae radiating from the center of the lesion are also commonly present. These oral lesions are indicative of what autoimmune disease? A) Mucous membrane pemphigoid, B) Pemphigus vulgaris, C) Lupus erythematosus, D) Bechet syndrome
Acute disseminated (Letterer Siwe): Affects children <3, chronic disseminated (Hand-Schuller-Christian): Skulls are radiolucent, solitary eosinophilic granuloma: Resembles perio disease
List 3 main forms of Langerhans Cell Histiocytosis (LCH) and provide one unique feature for each
Acute inflammation
Minimal injury with a short duration and ability to return to original state, or repair
The first statement is true. The second statement is false
Natural killer cell activity is a normal process the body activates to protect against viruses and cancer cells. Natural killer cells secrete antibodies and circulate throughout the body.
Root resorption
Observed radiographically when the apex of the tooth appears shortened or blunted and irregularly shaped
D) Aphthous ulcers
Oral lesions accompanying skin lesions may occur in the following diseases except one. Which is the exception? A) SLE, B) Pemphigus vulgaris, C) Lichen planus, D) Aphthous ulcers
C) Benign cementoblastoma
Pain is a frequent symptom of which lesion? A) Periapical cemento-osseous dysplasia, B) Central ossifying fibroma, C) Benign cementoblastoma, D) Odontoma
C) Salivary gland
Patients who have undergone radiation therapy for malignant tumors of the head and neck often experience severe xerostomia as a result of radiation dame to BLANK tissue: A) Oral mucosa, B) striated muscle, C) salivary gland, D) tooth
Neutrophils
Polymorphonuclear leukocytes which consists of 60-70% of all white blood cells and are derived from stem cells in bone marrow
B) Only salivary and lacrimal gland involvement occurs without the presence of another autoimmune disease
Primary Sjogren syndrome occurs when: A) Another autoimmune disease accompanies salivary and lacrimal gland involvement, B) Only salivary and lacrimal gland involvement occurs without the presence of another autoimmune disease, C) Rheumatoid arthritis is present, D) Raynaud phenomenon is present.
Bone marrow, attack antigens
T-cell lymphocytes develop from BLANK cells and function to BLANK
B) Constriction of the microvasculature
The first microscopic event in the inflammatory response is: A) Decreased blood flow, B) Constriction of the microvasculature, C) Phagocytosis, D) Dilation of microvasculature
Pemphigus vulgaris
The first signs of BLANK occur in the oral cavity in more than 50% of cases. Clinical signs include shallow ulcers, fragile vesicles, and/or bull
A) Both statements are true
The inflammatory response is a dynamic process, continually changing in response to injury and repair. Repair of tissue occurs only if the persistent source of injury is removed: A) Both statements are true, B) Both statements are false, C) The first statement is true; the second is false, D) The first statement is false; the second is true
C) Surgical excision
The most appropriate treatment for epithelial dysplasia is A) Radiation therapy, B) Chemotherapy, C) Surgical excision, D) Observation
Xerostomia
The most characteristic oral manifestation of Sjogren syndrome is
C) Gingiva
The most common location of intraoral Kaposi sarcoma is the A) Floor of the mouth, B) Tongue, C) Gingiva, D) Buccal mucosa
C) Rhabdomyosarcoma
The most common malignant soft tissue tumor of the head and neck in children is A) Squamous cell carcinoma, B) Chondrosarcoma, C) Rhabdomyosarcoma, D) Osteosarcoma
Injury
The result of an alteration in the environment that causes tissue damage or necrosis
Purulent exudate
Thick white-to-yellow pus containing tissue debris and many white blood cells
D) Has a better prognosis
Verrucous carcinoma is differentiated from squamous cell carcinoma because it A) Occurs primarily on the hard palate, B) Responds to chemotherapy, C) Often metastasizes, D) Has a better prognosis
C) Floor of the mouth, ventrolateral tongue, and soft palate
What are the most common sites for squamous cell carcinoma? A) Labial mucosa, buccal mucosa, and hard palate, B) Labial mucosa, maxillary gingiva, and buccal mucosa, C) Floor of the mouth, ventrolateral tongue, and soft palate, D) Anterior tongue, gingiva, and retromolar area
Fingers and toes
What parts of the body are involved in the Raynaud phenomenon?
III
What type of hypersensitivity reaction is involved in a fixed drug eruption when it occurs in the oral cavity?
D) Frequently fatal
Which is NOT a characteristic feature of benign ameloblastoma? A) Benign, B) Locally aggressive, C) Unencapsulated, D) Frequently fatal
A) Basal cell carcinoma
Which malignant skin tumor has the best prognosis? A) Basal cell carcinoma, B) Squamous cell carcinoma, C) Melanoma, and D) Epidermoid carcinoma
T-cell lymphocytes
Which of the following cells is not known to function as an antigen-presenting cell within the immune system?
C
Which of the following is FALSE regarding c-reactive proteins? A) A pro-inflammatory biomarker for systemic lupus and rheumatoid arthritis, B) Produced in the liver, C) A Hs-CRP Value greater than 3 indicates an average risk for cardiovascular disease, D) A pro-inflammatory biomarker for systemic lupus erythematosus
C
Which of the following is FALSE regarding c-reactive proteins? A) A pro-inflammatory biomarker for systemic lupus erythematous and rheumatoid arthritis. B) A protein produced in the liver. C) A Hs-CRP Value greater than 3 indicated a low risk for cardiovascular disease. D) A pro-inflammatory biomarker cardiovascular disease
D) Lupus erythematosus
Which of the following is a pathologic condition producing a characteristic butterfly-shaped lesion on the face and oral ulcers, occurs more frequently in females than males, and for which the result of a blood test is important in its diagnosis: A) Pemphigus, B) Erosive lichen planus, C) Desquamative gingivitis, D) Lupus erythematosus
Lupus erythematosus
Which of the following is a pathologic condition producing a characteristic butterfly-shaped lesion on the face and polar ulcers, occurs more frequently in females, and for which the result of a blood test is important in its diagnosis?
A) Exophytic erythroleukoplakia
Which of the following represents an early clinical example of squamous cell carcinoma? A) Exophytic erythroleukoplakia, B) Urticaria, C) Brown macule, and D) Destructive radiolucency
A) Adenoid cystic
All carcinomas are malignant tumors that originate from squamous epithelium except one. Which is the exception? A) Adenoid cystic, B) Basal cell, C) Verrucous, D) Squamous cell
Major aphthous ulcers
All of the following are examples of hypersensitivity reactions except
A) Major aphthous ulcers
All of the following are examples of hypersensitivity reactions except: A) Major aphthous ulcers, B) Urticaria, C) Angioedema, D) Contact dermatitis and mucositis
C) Basal cell carcinoma
All of the following arise in the oral cavity except one. Which one is the exception? A) Squamous cell carcinoma, B) Malignant melanoma, C) Basal cell carcinoma, D) Verrucous carcinoma
B) Tissue returns to its original state
All of the statements refer to chronic inflammation except one. Which is the exception? A) Duration may last weeks, months or years, B) Tissue returns to its original state, C) Heals less readily, D) Associated with functional deficiencies
A) Antibodies from a mother pass through the placenta to the developing fetus
An example of natural passive immunity occurs when: A) Antibodies from a mother pass through the placenta to the developing fetus, B) A microorganism causes a disease, C) A person receives a vaccination, D) A person is immunized
A) I
Anaphylaxis occurs as a result of what type of hypersensitivity: A) I, B) II, C) III, D) IV
B) 2 weeks
As a general rule, a patient should be referred to an oral and maxillofacial surgeon or dermatologist to have a biopsy performed on any non healing ulcer of the skin or lips that has been present for more than: A) 24 hours, B) 2 weeks, C) 3 months, D) 1 year
Pedunculated
Attached by a stem-like or stalk-like base similar to that of a mushroom
Stem, travel to sites where the antigen is.
B-cell lymphocytes develop from BLANK cells and function to BLANK
Injury to area, constriction of blood vessels, dilation and hyperemia of blood vessels, increase in permeability, low protein plasma, migration of WBC's, pavement of WBC's, emigration of WBC's, and emigration of purulent exudate
Describe the inflammatory process from initial injury to the emigration of purulent exudate
2-4; ipsilateral; no distant
According to the TNM staging system for oral squamous carcinoma, T2, N1, M0 would mean tumor BLANK cm in diameter, BLANK palpable nodes, and BLANK metastasis
Innate- Does not have memory. The body creates the response on its own. Acquired- Does have memory of antigens and acquires it from other things or people.
Describe the difference between innate and acquired immune response
D) Osteomyelitis
Each condition is an example of an oral immunologic disorder except one. Which one is the exception? A) Aphthous ulcers, B) Erythema multiforme, C) Fixed drug eruptions, D) Osteomyelitis
Serous exudate
Excess exudate which flows out of tissue as thin, clear fluid
