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When looking at known writings from 2000 years ago, which of the following uses for cannabis appears the most often? A. Use to treat pain B. Use to treat infectious diseases C. Use was discouraged, even 2000 years ago D. Use in religious visions

A

Which of the following FDA approved drugs is plant based? A. Epidiolex B. Syndrox C. Marinol D. Cesamet

A

Which of the following correctly describes the pH of the cannabis plant? A. Acid B. pH 7 C. It depends on the species D. Basic

A

Which of the following is not a part of motivational interviewing? A. Telling a patient what they must do B. Rolling with resistance C. Expressing empathy D. Avoiding disagreement

A

A patient has had success with zolpidem (Ambien) for sleep induction, but the physician won't prescribe any more, due to constant use and concern about substance use disorder. The patient says she has no trouble staying asleep, it's just falling asleep that is a problem. Which of the following hybrids is the most appropriate for this patient? A. Gorilla Glue #4 B. Zkittlez type 1 C. Skunk #1 D. Platinum Cookies

A

A patient with severe osteoarthritis of the knees also has COPD. He wants to try cannabis for the severe knee pain. What advice can you give him? A. Try topical or oral cannabis. Smoking/Toking/Vaping can complicate the COPD B. There is no evidence to support the use of cannabis in osteoarthritis C. You may not use cannabis because of the pre-existing COPD D. Be sure to find a cannabis product high in cannabicyclovarin (CBLV) to get the best results

A

An acquaintance says that she is making her own cannabis tincture. She uses a high-tech spice grinder, specialized filters and has her product assessed by a laboratory. All signs point to this being a high-quality product. Your friend is concerned that the tincture causes oral discomfort on dosing. What is the recommendation to help? A. Mix the dose with an ounce of honey B. Freeze the tincture so that it is very cold when dosing C. Place the intended dose into chocolate syrup D. Use methanol rather than ethanol in creating the tincture

A

Approximately what % of all cannabis users develop a substance use disorder? A. 9% B. 30% C. 50% D. 90%

A

Are cannabinoids helpful in treating post-traumatic stress disorder (PTSD)? A. There is limited evidence that nabilone could be helpful B. There is significant evidence that dronabinol is useful in treating PTSD C. There is limited evidence that cannabinoids are NOT helpful D. There is significant evidence that cannabinoids are harmful to these patients

A

CB-2 receptors are primarily located in which part of the body? A. PNS - peripheral nervous system B. GI - gastrointestinal tract C. all of the above are equal D. CNS - central nervous system

A

Cannabis was listed in the 1850 United States Pharmacopeia (USP). Which of the following companies made a cannabis product in 1850? A. Eli Lilly B. GW Pharma C. Merck D. Pfizer

A

Delta-9-tetrahydrocannabinol (THC) is the major psychoactive component of cannabis. Which of the other cannabinoids may be psychoactive? A. cannabicyclol (CBL) B. cannabiorcol (CBN-1) C. cannabadiocol (CBD-1) D. delta-8-tetrahydrocannabinol

A

Each of the following is an historic name for medical cannabis except __________? A. Da Gen B. Kunnabis C. Vijaya D. Shemshemet

A

Of the following terpenes, which is the least likely to be sedating? A. humulene B. myrcene C. caryophyllene D. terpinolene

A

The majority of patients who have tried cannabis, used it for which reason? A. Pain B. Recreational use C. Multiple sclerosis D. Sleeplessness

A

True or False? A prescriber wants a patient to try cannabidiol (CBD) for sleep. The prescriber may write a prescription for Epidiolex for that patient. A. True B. False

A

True or False? Because Epidiolex is a plant based drug, it is possible that a patient using Epidiolex will test positive for THC. A. True B. False

A

True or False? In states with legalized medical cannabis, opioid over-dose deaths have decreased. A. True B. False

A

True or False? Smoking / toking / vaping cannabis demonstrates an increase in cases of lung disease with chronic cough and excessive phlegm production. A. True B. False

A

True or False? There is currently no evidence to support or to refute the choice to use cannabis as a way to treat substance use disorder. A. True B. False

A

Under which Presidential administration was marihuana classified as a Controlled Substance in Schedule I? A. Nixon B. Truman C. Kennedy D. Lyndon Johnson

A

What route of administration was highlighted in the Ebers Papyrus? A. Vaginal B. Oral C. Inhalation D. Rectal

A

Which of the following statements is TRUE concerning cannabis? A. There have been no known fatal overdoses B. Cannabis can be used the same in people and in animals C. Cannabis is a plant that is safe for everyone to use D. There are no potentially harmful side effects when using cannabis

A

Which of the following was written by ibn Sina and used as a medical reference into the 1700's? A. The Canon of Medicine B. The Materia Medica C. The Ebers Papyrus D. Pen Ts'ao Ching

A

Why is the use of edibles safer than the use of vaping/smoking/toking? A. Edibles eliminate the risk of air-borne exposure that occurs with vaping/smoking/toking B. Oral use has no known side effects C. Oral use has never demonstrated substance use disorder D. here is NO safety benefit with oral product

A

Why is vaping still a viable delivery method since EVALI is a very real disease? A. The risk of EVALI decreases if patients use only whole plant in vaping devices B. EVALI is a chronic use disease, it does not occur with non-routine dosing C. EVALI only occurs in males under the age of 42 D. There are special vape filters to prevent EVALI

A

Why, when you are talking with a patient, do you ask if they have smoked / toked/ or vaped anything in the previous 90 days? A. You are looking to evaluate EVALI risks B. Because you don't care about ingested (eaten) cannabis C. Because it makes you sound really smart D. Because you want to promote nicotine cessation

A

You are conducting a literature search and find 4 articles that may be useful in answering a patient's question. What information will you find in the abstracts that may be helpful to deciding if you want to read them? A. A synopsis of the article B. The author's opinion C. A listing of the author's university affiliations D. Comments on the weaknesses in the presented study

A

You are living in Louisiana. You want to use medical cannabis. True or False? It is legal there. A. True B. False

A

You are searching the internet for information on medical cannabis. Which of the following sources is the most likely to contain quality information? A. A summary article based on a large number of previously published information B. A single author, single report C. The manuscript from a multi-center controlled study D. A synopsis of a controlled study

A

You are working with a patient who has traumatic brain injury from riding a motorcycle without a helmet. What evidence do we have for cannabis? A. There is limited evidence that cannabinoids will result in a better outcome B. There is significant evidence that cannabis will NOT be useful C. There is significant evidence that cannabis will help D. There is limited proof that cannabis will NOT be helpful

A

You have the following hybrids available in your cannabis pharmacy. Which would you recommend to a patient who wants to relax after work? A. Harlequin type 2 B. Skunk #1 C. Golden Pineapple type 1 D. Platinum Cookies

A

When considering using cannabis for symptoms of Tourette's Syndrome. Which route of administration has limited evidence to support use? A. Smoking/toking B. Oral C. Topical D. Vaping

B

A patient is looking for a hybrid that will substitute for Ganja Green, a hybrid he experienced in Amsterdam. He says it just made him feel happy and goofy. Which of the following hybrids is the most likely to cause a similar reaction? A. Harlequin type 2 B. Golden Pineapple type 1 C. ACDC type III D. Zkittlez type 1

B

A patient wants to try cannabis to treat inflammation from tennis elbow. Which combination of cannabinoid and terpene would be the best recommendation? A. cannabichromevarin + limonene B. cannabidiolic acid + bisabolol C. cannabicyclovarin + eucalyptol D. cannabifuran + humulene

B

Cannabis became popular in the British Islands because of the writings of Dr. William Brook O'Shaughnessy. Where did he learn about the medical uses for cannabis? A. Pakistan B. Calcutta C. Egypt D. Germany

B

Chronic use of cannabis can result in Cannabis Hyperemesis Syndrome (CHS). Which component of cannabis is believed to be the source of this condition? A. CHS is a terpene effect B. delta-9-tetrahydrocannabinol (THC) C. cannabidiol (CBD) D. all cannabinoids can cause CHS

B

For which of the following conditions should cannabis NEVER be recommended? A. epilepsy B. Morning Sickness of pregnancy C. HIV wasting disease D. Multiple sclerosis E. PTSD

B

In the Hindu religion, how is Bhang used? A. it is smoked in a traditional "bhang den" B. as a beverage served at festivals C. as a psychoactive drug use to meet "higher beings" D. it is a dessert reserved for sacred rites

B

In traditional Chinese medicine, which part of the cannabis plant is used? A. Stems B. Whole plant C. Flowers D. Leaves

B

Is the over-the-counter (OTC) sale of cannabidiol (CBD) legal in Nebraska today? A. No, it may only be sold by prescription B. Yes, if it's derived from hemp C. Yes, without restriction D. No, Nebraska does not have any legal cannabinoids

B

Roommates are both using Skunk #1 in vaporizing devices. The 1st roommate says it helps him write better music and enjoy life. The 2nd roommate says he is not a fan, all that Skunk #1 does from him is put him to sleep. How is it possible for these 2 to have such different experiences? A. The 2nd roommate is telling the truth, the 1st roommate is not being truthful B. The 2nd roommmate is using a larger dose than the 1st roommate C. The 1st roommate is telling the truth, the 2nd roommate is not being truthful D. The 1st roommate is using a larger dose than the 2nd roommate

B

The initial American restriction on cannabis came as the result of which law? A. The Pure Food and Drug Act of 1909 B. The Marihuana Tax Act of 1937 C. The USP Decommissioning Amendment of 1941 D. The International Narcotics Treaty of 1957

B

True or False? A patient who has been using cannabidiol (CBD) for several years to sleep, moved to a jurisdiction where CBD is not allowed. So she stopped taking the CBD and has experienced very poor sleep, This is evidence that she was addicted to the CBD. A. True B. False

B

True or False? Cannabis exerts its impact on humans only at cannabinoid receptors. A. True B. False

B

True or False? Cannabis has no known medical use. A. True B. False

B

True or False? Patients who use only CBD products will not test positive for THC on a drug test. A. True B. False

B

True or False? Smoking / toking / vaping cannabis demonstrates an increase in cases of lung cancer. A. True B. False

B

True or False? Smoking, toking, or vaping cannabis is known to cause lung cancer. A. True B. False

B

True or False? The impetus for regulating cannabis was the result of the American Medical Association lobbying against its use. A. True B. False

B

True or False? The majority of people who have tried cannabis ultimately develop a substance use disorder. A. True B. False

B

True or False? The most commonly abused illicit substance in Nebraska, after alcohol by minors, is cannabis A. True B. False

B

True or False? There is no test for "cannabis levels" in the blood, so you cannot be charged with "driving under the influence" of cannabis. A. True B. False

B

True or False? Using cannabis is a gateway to escalating illicit drug use, particularly the use of methamphetamine. A. True B. False

B

True or False? When reviewing a study in the literature, the best studies have no listed weaknesses. A. True B. False

B

True or False? When using cannabis to treat arthritis in pets and livestock, it is best to use a weight ratio. E.g. the dose for a 200-pound man should be quadrupled to dose an 800-pound horse. A. True B. False

B

What is a key element in the decision to recommend cannabis in a patient with an alcohol substance use disorder? A. The patient must be female B. The patient must guarantee total alcohol abstinence C. The patient must be over 65 years of age D. The patient must be under 35 years of age

B

When looking at known writings from 2000 years ago. Which of the following uses for cannabis appears the most frequently? A. The use was discouraged, even 2000 years ago B. Treatment for pain C. Treatment of infectious diseases D. Religious visions

B

Which cannabinoid is most known for causing "the munchies"? A. CBN B. THC C. CBD D. CBE

B

Which exit is it, where 1/2 of the population of Nebraska is in your rear-view mirror and 1/2 the population is in front of you. Remember, you are driving on Interstate 80 from Omaha to Wyoming. A. The Beaver Crossing Exit B. The Gretna Exit C. The Seward Exit D. The York Exit E. The Lincoln Exit

B

Which hydrocarbon is useful in extracting cannabinoids from the cannabis plant? A. methyl alcohol B. butane C. propane D. octane

B

Which of the following has substantial evidence for the effective use of cannabis? A. Amyotrophic lateral sclerosis (ALS) B. Chronic pain C. Anorexia nervosa D. Epilepsy

B

Which of the following is NOT a species of cannabis? A. Sativa B. Tumerica C. Ruderalis D. Indica

B

Which of the following is NOT an FDA approved cannabinoid? A. Marinol B. Sativex C. Cesamet D. Epidiolex

B

Which of the following is true concerning cannabis and mental health? A. Cannabis is not appropriate for people with social anxiety B. Heavy cannabis use is associated with an increase in suicidal ideation C. Cannabis use increases the risk of depression D. Cannabis with higher levels of CBD and CBN are useful in patients with dementia

B

Which of the following is true concerning the use of cannabinoids for multiple sclerosis? A. patients struggle with the side effects making this product unuseful B. patients report improved spasticity C. patients don't notice a difference, but lab results show an improvement D. clinicians report an improvement in spasticity

B

Which of the following warnings on over-use of cannabis is over 1000 years old? A. cannabis can increase fertility B. cannabis can cause visions C. cannabis can cause lung damage D. cannabis can cause schizophrenia

B

Which was the 1st state to allow for medical cannabis after the marihuana tax act was passed? A. Hawaii B. California C. Michigan D. Alaska

B

Why does the human body have cannabinoid receptors? A. This is a scientific mystery B. Humans make endocannabinoids that act at these receptors C. Humans do not have cannabinoid receptors D. These are products of evolution from animals that ate cannabis

B

Why is Cannabis sativa the only species recognized as hemp? A. It cannot be used medically B. It grows the tallest, providing long fibers for rope C. It flowers independently of sunlight, allowing for multiple harvests per year D. It has the lowest THC:CBD ratio

B

A parent of a child with attention deficit and hyperactivity disorder (ADHD) is afraid to give her child Adderall (a prescription stimulant, indicated for the treatment of ADHD) because she read on Facebook that it increases the risk for recreational cannabis use in her child. What does the science say? A. She has every reason to worry, thank goodness she read it on Facebook! B. There is inadequate science to calm her fears C. There is substantial evidence that this is not true D. There is limited proof that cannabinoids will counteract the Adderall

C

A patient is being treated for substance use disorder and is currently in full abstinence from alcohol and oxycodone. The patient is being treated with buprenorphine and group counseling. She also participates in 12-step meetings at least 5 times weekly. She wants to try CBD gummies for sleeplessness. What is your recommendation? A. The CBD is a good choice, but start with a low dose and increase only if necessary B. the CBD is currently cautioned C. The CBD is currently contraindicated D. CBD is not effective in insomnia

C

A patient with severe nightmares from PTSD is looking at using Harlequin type 2 for sleep. She has been told that it is great for muscle relaxation and sleep. She has a vaporizing device and wants to try that. What will you tell her? A. This is NOT the hybrid you want to try because it will make the PTSD worse B. Platinum cookies would be a much better choice for you C. If you vape this hybrid, it may not last for an 8 hour sleep D. Be very careful, this hybrid is noted to cause hallucinations

C

An anti-cannabis protester is arguing that the legalization of cannabis will result in a dramatic increase in the number of people with cardiovascular disease. She is particularly vocal that this will be cardiovascular disease in people who shouldn't have it. Which of the following is true about cannabis and the cardiovascular system? A. Cannabis can damage major arteries such as the aorta or carotids B. Cannabis can cause elevated cholesterol C. Cannabis can cause increased heart rate D. Cannabis is associated with an increased risk of heart attack in people over the age of 61 years

C

CB-1 receptors are primarily located in which part of the body? A. Peripheral Nervous System (PNS) B. Gastrointestinal Tract (GI) C. Central Nervous System (CNS) D. All of the above are equal

C

CBD has similar effects on drug metabolism as which of the following? A. a prescription beta-blocker B. Jalapeno pepper C. Grapefruit D. a prescription diuretic

C

NASEM commented on the use of which cannabis product for the treatment of irritable bowel disease? A. anandamide B. GPR119 C. dronabinol D. cannabidiol

C

One of the challenges in studying cannabis is that the psychoactive effects of the drug cannot be hidden. Which of the following is a potential problem if patients know they are receiving active drug? A. They may tell the researcher how to evaluate them B. Those patients must be removed from the study and that decreases the data available to be evaluated C. They may over-report adverse effects, blaming everything they feel on the drug D. They may under-report adverse effects because they want to keep taking the drug

C

Since the "counterfactual ideal" in study design cannot be realized, what is the gold-standard for drug study design? A. A long-term study where patients are monitored every 2 weeks for at least 52 weeks B. A retrospective data review allowing for cohort matching C. A randomized, placebo controlled clinical trial D. A well-matched observational study of over 10,000 people

C

The Ben Jing is based on the work of ______________? A. Ma Fen B. Hatshepsut C. Emperor Shen Nong D. Ben Jing

C

The FDA specifically prohibits the advertising of cannabis for which condition? A. asthma B. hyperemesis gravidarum C. cancer D. glaucoma

C

The librarian from McGoogan library recommends using the "CRAAP" test to determine if you are looking at high quality information. What does the "C" stand for? A. Cannabis or Cannabinoids B. Controlled C. Current or Timely D. Co-authored by more than 1 profession

C

What is the current Federal schedule of "Marihuana"? A. Schedule III B. Schedule II C. Schedule I D. Schedule IV

C

What is the ocular concern when recommending cannabis? A. Loss of eyelashes from vaping B. Increased intraocular pressure from THC C. Increased intraocular pressure from CBD D. Weakening of eye muscles and nystagmus

C

What is the term used to describe the pharmacologic effects of whole plant that cannot be found when using individual components? A. Fractional effect B. Aggregate effect C. Entourage effect D. Deficient effect

C

What was the legal status of cannabis in 1619 in the Virginia Colonies? A. All public house (pub) owners were required to sell it B. It was legal for medical uses only C. It was required that all landowners grow cannabis D. It was legal for recreational uses only

C

Which of the following is a DUTY of the health care professional discussing the medical use of cannabinoids and cannabis? A. To give the patient the best possible price B. To report all illegal activity to law enforcement C. To be honest D. To make the patient feel comfortable

C

Which of the following is an immediate impact of cannabis? A. cannabinoid hyperemesis syndrom (CHS) B. improved night driving skills C. impaired short-term memory D. decrease in sexually transmitted infections

C

Why is cannabis currently contraindicated with opioids? A. loss of pain control B. decreased opioid metabolism C. increased risk of respiratory depression D. increased risk of substance use disorder

C

Why is cannabis used in caution with people using anabolic steroids? A. decreased blood levels of the steroid B. decreased metabolism of the cannabis C. decreased metabolism of the steroid D. increased risk of fetal malformation

C

World-wide nabiximols are used sublingually to treat what condition? A. Insomnia of grief B. Morning sickness and hyperemesis gravidarum C. Muscle spasms associated with Multiple Sclerosis D. Nausea and vomiting from cancer chemotherapy

C

You are conducting research on cannabis in the Kush Mountains. Which of the following species of cannabis is native there? A. Cannabis gunjai B. Cannabis sativa C. Cannabis indica D. Cannabis ruderalis

C

You are counseling a pregnant patient about the use of cannabis during her pregnancy. Each of the following concerns should be address, except which? A. Complications of pregnancy B. childhood sleep problems for the baby C. Decreased maternal post-partum weight D. Lowered birth weight for the baby

C

A child with intractable seizures is going to start taking prescription Epidiolex (CBD). What should the pharmacist monitor when the Epidiolex is started? A. The child may lose the ability to speak B. Blood levels of existing antiepileptic drugs may decrease C. The child may have increased periods of sleeplessness D. Blood levels of existing antiepileptic drug may increase

D

A patient asks you about Kunnabis Periwinkle strain 15. What is the best response to these questions? A. All of the indica strains are similar B. it's sorta like Maui Blue, but with less CBD C. That's a recreational product with no known medical benefits D. I don't know anything about this strain, but I am happy to check and get back to you

D

Cannabidiol (CBD) is known to cause significant drowsiness. Which other cannabinoid is known to cause this same reaction? A. cannabicyclol (CBL) B. cannabigerol (CBG) C. cannabielsoin (CBE) D. cannabinol (CBN)

D

Cannabidiol (CBD) opposes or moderates the effects of delta-9-tetrahydrocannabinol (THC). Which terpene can serve the same purpose? A. limonene B. linalool C. bisabolol D. pinene

D

For which of the following substances is cannabis known as an "environmental cleaner"? A. heavy metals B. pesticides C. herbicides D. Each of these is correct

D

Hua Tuo used cannabis in combination with which therapy, now called CAM (Complimentary Alternative Medicine)? A. Aroma Therapy B. Hypnosis C. Yoga D. Acupuncture

D

On which continent did cannabis originate? A. North America B. Australia C. Africa D. Asia

D

One way to address whether or not a study subject can identify if s/he is taking active drug or placebo is to ask them to guess what they have received. Which of the following is true regarding this question? A. If a majority surmise incorrectly, the study author should not report this B. If the majority surmise incorrectly, you may assume that no one knew which product they were receiving C. If a majority surmise correctly, all of the data from the study are useless D. If a majority surmise correctly, that must be reported in the study findings

D

Patients and study-subjects may act differently because they are a part of a study. This complicates the analysis of the results. What is this confounding variable called? A. Internal Bias B. A Counterfactual Conundrum C. The Cochran Anachronism D. The Hawthorne Effect

D

Recreational cannabis is legal in which of the following? A. New Hampshire B. Alabama C. Idaho D. Washington DC

D

What is the current Federal schedule for cocaine? A. Schedule I B. Schedule IV C. Schedule III D. Schedule II

D

What processes do endocannabinoids impact within humans? A. memory B. homeostasis C. pain D. Each of these is correct

D

When is it appropriate to lie to a patient about cannabis? A. If they ask you about your use B. If you suspect that the patient is using cannabis C. When you are afraid the patient will be harmed by cannabis D. Never

D

Which cannabaceae species is very short with low THC and high CBD content? A. Cannabis sativa B. Cannabis indica C. Cannabis celtis D. Cannabis ruderalis

D

Which disease are cannabis users, who begin using before the age of 15, at increased risk of being diagnosed with? A. hyperlipidemia B. anorexia C. hypothyroidism D. schizophrenia

D

Which of the following does NOT have sufficient evidence for the effective use of cannabis? A. Chemotherapy-induced nausea and vomiting B. Multiple sclerosis spasticity symptoms C. Short-term sleep disturbance related to fibromyalgia D. Abstinence from addictive substances

D

Which of the following is the best description of an "infodemic"? A. It's a made-up word intended to scare people about SARS-CoV-2 B. It's a media blast from the CDC (Centers for Disease Control and Prevention) with significant health warnings C. It's a made-up word intended to make people calm when there is a pandemic D. So much information that it is hard to tell which is accurate and which is hype

D

Which was the 1st state to allow for recreational cannabis after the marihuana tax act? A. California B. Connecticut C. North Carolina D. Colorado

D

Who is responsible for scheduling cannabis containing drugs? Recall that scheduling is a legal indication that the drug may be habit forming. A. The Board of Pharmacy B. The Bureau of Alcohol, Tobacco, and FireArms C. The FDA D. The DEA

D

Who was the primary bureaucrat who fought for the regulation of marihuana during the 1940's? A. Herbert Hoover B. J. Sterling Morton C. William Randolph Hearst D. Henry Anslinger

D

Why does vaping pose an over-dosing risk when compared to smoking? A. Because vaping is legal where toking isn't B. It has a slower onset than smoking, thus resulting in over-use C. Vaping liquids are always highly concentrated D. Because it tastes better

D

Why is alcohol contraindicated with cannabis? A. increased risk of hallucinations B. increased risk of substance use disorder C. just what the world needs is someone stoned and drunk! D. additive depressant effects E. decreased renal clearance of the cannabinoid

D

You are taking with a patient, who used to shop at your cannabis pharmacy, but left you several months ago. He is sheepishly telling you that he'd like to come back to your store. he says that when he bought ACDC-III from you that it worked very well for peripheral neuropathy, but the ACDC-III he bought at Louie's Bait Shop doesn't relieve these symptoms. How is this possible? A. There are no labeling laws standardizing the labels on cannabis products B. Louie's product was stored incorrectly C. He got a different plant from the Bait Shop D. All of these answers are possibilities

D

Which of the following are components of cannabis? A. omega fatty acids B. terpenes C. cannabinoids D. flavonoids E. Each of these is correct

E


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