Pharma
All of these substances are part of the body's own natural blood pressure- regulating systems
(1) Angiotensin II (2) Epinephrine (3) Angiotensin I
Drugs used to treat angina pectoris include all the following
(1) Calcium Channel Blocker (2) Nitrate Drugs (3) Beta- Blocker Drugs
Calcium channel blocker drugs block the movement of calcium ions into the heart muscle and smooth muscles in the blood vessels. This results in what actions
(1) Decreasing the heart rate (2) Lowering Blood Pressure (3) Dilating the Artires
High levels of cholesterol in the blood can be due to
(1) Dietary Intake of egg yolks, bacon, cream and lard (2) A generic disorder (3) Eating foods high in cholesterol
When a toxic effects occur, the physician can respond by
(1) Discontinuing the drug (2) Decreasing the dose (3) Lengthening the time between doeses
An antagonist drug
(1) Is similar to inserting the wrong key in a lock (2) Keeps other drugs from activating the receptor (3) Occupies but does not activate a receptor
Side effects can be
(1) Mild and temporary (2) Moderate and annoying (3) Severe enough that the drug must be stopped
Nitroglycerin is available in all of the following drug forms
(1) Ointment (2) Sublingual Tablet (3) Transdermal Patch
Digitalis drugs
(1) Slow heart rate (2) Help treat CHF (3) Make it beat stronger
Alpha-Blocker
-azosine
Calcium Channel Blocker
-ipine
Beta-Blocker
-olol
ACE Inhibitor
-pril
Angiotensin II receptor blocker
-sartin
HMG-CoA reductase inhibitor
-statin
A drug is able to unlock or activate a receptor and produce an effect is known as a/an
Agonist
A drug that can unlock or activate a receptor is known as a/an
Agonist
HMG-CoA reductase is
An enzyme that is involved in one of the steps in the production of cholesterol in the body
Hypertension is characterized by
An increase in the systolic and/or diastolic blood presure
A list of the common side effects of a new drug is developed
As the new drug is being testedd
If serum cholesterol levels are too high, bile acid sequestrant
Bind toe bile to form an insoluble complex that is excreted in the feces
What category of drugs blocks the action of epinephrine at beta1 receptors in the heart
Cardioselective beta blocker drugs
To decrease the pain of angina pectoris, effective drugs
Decrease the heart rate, which decreases the myocardium's need oxygen
High levels of HDL are High levels of LDL are
Desirable Undesirable
The drug used to treat congestive heart failure is
Digoxin
Nitrate Drugs
Dilate the coronary arteries and increase the flow of oxygenated blood to the myocardium
The step care approach to treating hypertension involves the initial prescribing of what category of drug
Diuretic Drugs
What class of drugs promote the excretion of sodium and water to decrease the total blood volume and lower the blood pressure
Diuretic Drugs
Hyperlipidemia is a category that encompasses
Hypercholesterolemia and Hypertriglyceridemia
HTN stands for
Hypertension
To be transported through the blood, cholesterol and triglycerides must bind to certain carrier molecules, known as
Lipoproteins
Toxic effect are most comm in elderly patients whose _______ are less able to metabolize and excrete a drug
Liver and Kidneys
The pain of angina pectoris occurs because
Of insufficient oxygenated blood going to the cells of the myocardium
The therapeutic effect of a drug is usually exerted
On the target organ
Which of the following increase the likelihood of a drug-drug interaction
Polypharmacy
A drug-drug reaction in which the two drugs combine to produce an effect greater than the independent effect of each drug is called
Synergism
A toxic effect of a drug results when
The serum level of a drug rises above the therapeutic level
A drug's main action for which it was prescribed by the physician or other healthcare provider is known as a/an
Therapeutic Effect
When a drug has a narrow margin of safety between the correct dose and toxic dose, that drug is said to have a low
Therapeutic Index
Alpha-blocker drugs are used to treat hypertension because they block alpha receptors in both the arteries and veins because
They block alpha receptors in both the arteries and veins and cause them to dilate to lower the blood pressure
The systemic effect of a drug is felt
Throughout the body
Very low-density lipoproteins carry _______ in the blood
Triglycerides
ACE inhibitor drugs cause
vasodilation and decrease the blood pressure against which the heart must pump