BB Q#1

The results of a Kleihauer-Betke stain indicate a feto-maternal hemorrhage of 35 mL of whole blood. How many vials of Rh immune globulin would be required? A. 1 B. 2 C. 3 D. 4

B. 2

Lectins are useful in determining the cause of abnormal reactions in blood bank serology. These lectins are frequently labeled as anti-H, anti-A1 etc. The nature of these lectins is explained by which of the following? A. An early form of monoclonal antibody produced in nonvertebrates B. A plant substance that chemically reacts with certain RBC antigens C. Naturally occurring antibodies in certain plants D. The ability of plants to respond to RBC antigens by antibody production

B. A plant substance that chemically reacts with certain RBC antigens

What chain is formed when the terminal galactose on the ABH precursor substance is attached to the N-acetylglucosamine in beta 1, 4 linkage? A. Type 1 precursor chain B. Type 2 precursor chain

B. Type 2 precursor chain

A patient tests positive for weak D but also appears to have anti-D in his serum. What may be the problem? A. Mix up of samples or testing error B. Most weak D individuals make anti-D C. The problem could be due to a disease state D. A D mosaic may make antibodies to missing antigen parts

D. A D mosaic may make antibodies to missing antigen parts

A trauma patient with type AB is seen at a rural hospital. The hospital only has 3 units of type AB RBCs. What blood type of RBCs can the patient receive as an alternative? A. Type O B. Type B C. Type A D. None of the above E. All of the above

E. All of the above

A complete Rh typing for antigens C, c, D, E, and e revealed negative results for C, D, and E. How is the individual designated? A. Rh positive B. Rh negative C. Positive for c and e D. Impossible to determine

B. Rh negative

What techniques are necessary for weak D testing? A. Saline + 22°C incubation B. Albumin or LISS + 37°C incubation C. Saline + 37°C incubation D. 37°C incubation + indirect antiglobulin test

D. 37°C incubation + indirect antiglobulin test

Which blood group has the LEAST amount of H antigen? A. A1B B. A2 C. B D. A1 E. O

A. A1B

The glass surface of an Rh viewbox should be _____ C A. Between 45 and 50C B. Between 26 and 39C C. Between 16 and 25C D. Between 0 and 15C

A. Between 45 and 50C

Which of the following is the most common haplotype in the ASIAN population? A. DCe B. DcE C. Dce D. ce

A. DCe

An antigen present on most D-positive and all C-positive RBCs: A. G B. f C. rhi D. Cw

A. G

Transformation to Leb phenotype after birth may be as follows: A. Le(a-b-) to Le(a+b-) to Le(a+b+) to Le(a-b+) B. Le(a+b-) to Le(a-b-) to Le(a-b+) to Le(a+b+) C. Le(a-b+) to Le(a+b-) to Le(a+b+) to Le(a-b-) D. Le(a+b+) to Le(a+b-) to Le(a-b-) to Le(a-b+)

A. Le(a-b-) to Le(a+b-) to Le(a+b+) to Le(a-b+)

Which cells agglutinate most strongly with Ulex europaeus lectin? A. O B. A1 C. A1B D. A2B E. Oh (Bombay phenotype)

A. O

Which of the following is NOT true about the anti-A and anti-B? A. They are well-developed at birth B. They are "naturally occurring" C. They are IgM isoagglutinins D. They are reactive at cold temperature

A. They are well-developed at birth

If an Rh negative woman recently delivered an Rh positive baby and the Kleihauer-Betke test result is 5%, how many vials of Rh Ig should be administered? A. 6 B. 7 C. 8 D. 9

D. 9

If a patient has the Rh genotype DCe/DCe and receives a unit of red blood cells from a DCe/dce individual, what Rh antibody might the patient develop? A. Anti-C B. Anti-c C. Anti-d D. Anti-E

B. Anti-c

If a patient who is R1R1 is transfused with RBCs that are Ror, which antibody is he most likely to produce? A. Anti-D B. Anti-c C. Anti-e D. Anti-G

B. Anti-c

Rh antibodies are predominantly: A. IgM B. IgG C. IgD D. IgA

B. IgG

Which of the following characteristics best describes Lewis antibodies? A. IgM, naturally occurring, cause HDN B. IgM, naturally occurring, do not cause HDN C. IgG, in vitro hemolysis, cause hemolytic transfusion reactions D. IgG, in vitro hemolysis, do not cause hemolytic transfusions

B. IgM, naturally occurring, do not cause HDN

What should be done if all forward and reverse ABO results are negative? A. Perform additional testing such as typing with anti-A1 lectin and anti-A,B B. Incubate at 22°C or 4°C to enhance weak expression C. Repeat the test with new reagents D. Run an antibody identification panel

B. Incubate at 22°C or 4°C to enhance weak expression

Rh immune globulin provides ____ protection against fetal D antigen. A. Active B. Passive C. Antigen-stimulated D. Antibody-stimulated

B. Passive

What type of serological testing does the blood bank technologist perform when determining the blood group of a patient? A. Genotyping B. Phenotyping C. Both A & B D. PCR

B. Phenotyping

Anti-c can be formed by persons with the genotype: A. R1R2 B. R1R1 C. R2r D. rr

B. R1R1

From the following ABO mating, what are the probabilities of the ABO PHENOTYPES of potential offspring? Mother: Group O; Father: Group B (heterozygous) A. 50% BO, 50% OO B. 100% BO C. 50% B, 50% O D. 50% B, 50% A

C. 50% B, 50% O

An individual with genes A, H, Se and lele has which of the following phenotypes? A. ABH, Le (a-b-) B. ABH, Le (a+b-) C. AH, Le (a-b-) D. AH, Le (a+b-)

C. AH, Le (a-b-)

Which typing results are most likely to occur when a patient has an acquired B antigen? A. Anti-A 4+, anti-B-3+, A1 cells neg, B cells neg B. Anti-A 3+, anti-B neg, A1 cells neg, B cells neg C. Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+ D. Anti-A 4+, anti-B 4+, A1 cells 2+, B cells neg

C. Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+

ABH substances would be found in the saliva of a group B secretor: A. H B. A and H C. B and H D. A, B and H

C. B and H

Which of the following describes the expression of most blood group antigens? A. Dominant B. Recessive C. Codominant D. Corecessive

C. Codominant

N-acetyl-D-galactosamine is the immunodominant carbohydrate that reacts with: A. Arachis hypogaea B. Salvia sclarea C. Dolichos biflorus D. Ulex europeaus

C. Dolichos biflorus

"O" secretor person would demonstrate what substance/s in his saliva: A. A B. B C. H D. A and B

C. H

A stem cell transplant patient was retyped when she was transferred from another hospital. What is the most likely cause of the following results? Patient cells: Anti-A neg, Anti-B 4+ Patient serum: A1 cells neg, B cells neg A. Viral infection B. Alloantibodies C. Immunodeficiency D. Autoimmune hemolytic anemia

C. Immunodeficiency

If a person has the genetic makeup Hh, AO, LeLe, sese, what substance will be found in the secretions? A. A substance B. H Substance C. Lea substance D. Leb substance

C. Lea substance

In which of the following blood group systems may the red blood cell typing change during pregnancy? A. P B. MNS C. Lewis D. Duffy

C. Lewis

Anti-E will react with which of the following cells? A. RoRo B. R1R1 C. R2R2 D. rr

C. R2R2

What does the genotype ---/--- represent in the Rh system? A. Rh negative B. D mosaic C. Rh null D. Total Rh

C. Rh null

A patient's serum is incompatible with O cells. The patient RBCs give a negative reaction to anti-H lectin. What is the most likely cause of these results? A. The patient may be a subgroup of A B. The patient may have an immunodeficiency C. The patient may be a Bombay D. The patient may have developed alloantibodies

C. The patient may be a Bombay

ABO antibodies in infants are detected in serum: A. At birth in cord blood B. 2 to 4 weeks after birth C. 1 to 2 months after birth D. 3 to 6 months after birth

D. 3 to 6 months after birth

Rh antibodies react best at what temperature (°C)? A. 15 B. 18 C. 22 D. 37

D. 37

What blood type is not possible for an offspring of an AO and BO mating? A. AB B. A or B C. O D. All are possible

D. All are possible

What antibodies are formed by a Bombay individual? A. Anti-A and Anti-B B. Anti-H C. Anti-AB D. Anti-A, Anti-B, and Anti-H

D. Anti-A, Anti-B, and Anti-H

Of the red cells listed, which has the most D antigen present? A. Rh null B. D positive C. dce/dce D. D- - / D - -

D. D- - / D - -

The immunogenicity of the common Rh antigens may be described from greatest to least: A. D>C>E>c>e B. D>c>E>e>C C. c>D>C>E>e D. D>c>E>C>e

D. D>c>E>C>e

Acquired B antigens have been found in: A. Bombay individuals B. Group O persons C. All blood groups D. Group A persons

D. Group A persons

Which of the following sugars must be present on a precursor substance for A and B antigenic activity to be expressed? A. D-Galactose B. N-Acetylgalactosamine C. Glucose D. L-Fucose

D. L-Fucose

The antigen system closely associated phenotypically with Rh is known as: A. McCoy B. Lutheran C. Duffy D. LW

D. LW

Rh-HDN occurs in what type of mother and child: A. Mother and child are both Rh (-) B. Mother and child are both Rh (+) C. Mother is Rh (+), child is Rh (-) D. Mother is Rh (-), child is Rh (+)

D. Mother is Rh (-), child is Rh (+)

All are associated with Group I ABO discrepancies, except: A. Newborns and elderly patient B. Patients with congenital immunodeficiency diseases C. Patients using immunosuppressive drugs D. Subgroups of A or B

D. Subgroups of A or B

If a patient has an A2 ABO type, which of the following statements is true? A. The patient's red cells will react with anti-A1 lectin B. The patient's serum will react with A2 cells C. The patient's red cells will react with anti-A2 lectin D. The patient's serum will react with A1 cells if anti-A1 is present

D. The patient's serum will react with A1 cells if anti-A1 is present

Which genotype(s) will give rise to the Bombay phenotype? A. HH only B. HH and Hh C. Hh and hh D. hh only

D. hh only