Homework 2
Which of these descriptions best matches the functions of platelets?
Adhere to collagen beneath endothelium
_____ involves a cascade of reactions leading to the conversion of fibrinogen to fibrin.
Coagulation
How would removal of calcium ions from a blood sample affect coagulation?
Coagulation would be prevented
Hemophilia is a bleeding disorder in which the blood doesn't clot normally due to the lacking of certain _____.
blood clotting factors
The intrinsic pathway of the blood clotting is due to the damage of _____.
blood vessel
The process of fibrinolysis
dissolves clots
Tissue factor (Factor III) is a factor in the _____ pathway.
extrinsic
The final product of the common pathway of coagulation is _____.
fibrin thread
Which of the following is NOT a mechanism of hemostasis?
fibrinolysis
Some rat poisons contain a toxin that blocks the liver's ability to utilize Vitamin K. Animals that consume this poison would die of
hemorrhage
The cessation of bleeding is specifically called _____.
hemostasis
[More than 1 answer] A digestive disorder that impairs a person's ability to absorb Vitamin K will result in
low levels of prothrombin low levels of fibrin prolonged bleeding
Areas in a vessel wall where large quantities of lipid accumulate are called
plaques
The enzyme that can digest fibrin and dissolve a clot is
plasmin
The clotting factor that initiates the intrinsic pathway of coagulation is released by _____.
platelets
The extrinsic pathway of coagulation is initiated by the
release of tissue factor (Factor III) by damaged endothelium
Most of the protein factors that are required for clotting are synthesized by
the liver
Which of the following vitamins is needed for the formation of clotting factors?
Vitamin K
Which clotting factor(s) initiate the intrinsic pathway of coagulation?
XII
The intrinsic pathway of coagulation is activated by the
activation of Factor XII exposed to collagen
The positive feedback for amplifying the coagulation effect takes place in _____.
common pathway
The common pathway of coagulation begins with the
conversion of Factor X to prothrombinase
The conversion of fibrinogen to fibrin is catalyzed by the enzyme
thrombin
